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- $Unique_ID{BRK03407}
- $Pretitle{}
- $Title{Acanthocheilonemiasis}
- $Subject{Acanthocheilonemiasis Dipetalonemiasis}
- $Volume{}
- $Log{}
-
- Copyright (C) 1986 National Organization for Rare Disorders, Inc.
-
- 114:
- Acanthocheilonemiasis
-
- ** IMPORTANT **
- It is possible that the main title of the article (Acanthocheilonemiasis)
- is not the name you expected. Please check the SYNONYM listing to find
- alternate names and disorder subdivisions covered by this article.
-
- Synonyms
-
- Dipetalonemiasis
-
- General Discussion
-
- ** REMINDER **
- The information contained in the Rare Disease Database is provided for
- educational purposes only. It should not be used for diagnostic or treatment
- purposes. If you wish to obtain more information about this disorder, please
- contact your personal physician and/or the agencies listed in the "Resources"
- section.
-
-
- Acanthocheilonemiasis is a mild parasitic infection found in the tropics,
- most commonly in Africa. In temperate regions it is rare. The prognosis is
- favorable.
-
- Symptoms
-
- Acanthocheilonemiasis infections may be asymptomatic, or the patient may
- experience itching and hives, pain in the abdomen, chest, and legs, and
- dizziness. Sometimes there is fever. The spleen and liver are enlarged, and
- there may be edema. Laboratory findings include eosinophilia, elevated
- gammaglobulin fractions, and microfilariae from a parasitic worm in the
- blood. Pathologically, acanthocheilonemiasis consists of acute and chronic
- inflammation in response to the adult nematode, which lodges in the subserous
- tissues of the abdomen and thorax.
-
- Causes
-
- The causative organism is a filarial worm called either Acanthocheilonema
- perstans or Dipetalonema perstans. It is transmitted from one host to
- another by a small black midge known as A. Cailicoides.
-
- Therapies: Standard
-
- Diethylcarbamazine is the most satisfactory treatment. Surgical removal of
- large adult worms may be necessary. Mild cases may be left untreated. Please
- see article on Filariasis for further information.
-
- Therapies: Investigational
-
- This disease entry is based upon medical information available through
- September 1989. Since NORD's resources are limited, it is not possible to
- keep every entry in the Rare Disease Database completely current and
- accurate. Please check with the agencies listed in the Resources section for
- the most current information about this disorder.
-
- Resources
-
- For more information on Acanthocheilonemiasis, please contact:
-
- National Organization for Rare Disorders (NORD)
- P.O. Box 8923
- New Fairfield, CT 06812-1783
- (203) 746-6518
-
- NIH/National Institute of Allergy and Infectious Diseases
- 9000 Rockville Pike
- Bethesda, MD 20892
- (301) 396-5717
-
- Centers for Disease Control (CDC)
- 1600 Clifton Road, NE
- Atlanta, GA 30333
- (404) 639-3534
-
- References
-
- Diethylcarbamazine and new compounds for the treatment of filariasis. ADV
- PHARMACOL CHEMOTHER (1979) 16:129:94.
-
-