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$Unique_ID{BRK03407}
$Pretitle{}
$Title{Acanthocheilonemiasis}
$Subject{Acanthocheilonemiasis Dipetalonemiasis}
$Volume{}
$Log{}
Copyright (C) 1986 National Organization for Rare Disorders, Inc.
114:
Acanthocheilonemiasis
** IMPORTANT **
It is possible that the main title of the article (Acanthocheilonemiasis)
is not the name you expected. Please check the SYNONYM listing to find
alternate names and disorder subdivisions covered by this article.
Synonyms
Dipetalonemiasis
General Discussion
** REMINDER **
The information contained in the Rare Disease Database is provided for
educational purposes only. It should not be used for diagnostic or treatment
purposes. If you wish to obtain more information about this disorder, please
contact your personal physician and/or the agencies listed in the "Resources"
section.
Acanthocheilonemiasis is a mild parasitic infection found in the tropics,
most commonly in Africa. In temperate regions it is rare. The prognosis is
favorable.
Symptoms
Acanthocheilonemiasis infections may be asymptomatic, or the patient may
experience itching and hives, pain in the abdomen, chest, and legs, and
dizziness. Sometimes there is fever. The spleen and liver are enlarged, and
there may be edema. Laboratory findings include eosinophilia, elevated
gammaglobulin fractions, and microfilariae from a parasitic worm in the
blood. Pathologically, acanthocheilonemiasis consists of acute and chronic
inflammation in response to the adult nematode, which lodges in the subserous
tissues of the abdomen and thorax.
Causes
The causative organism is a filarial worm called either Acanthocheilonema
perstans or Dipetalonema perstans. It is transmitted from one host to
another by a small black midge known as A. Cailicoides.
Therapies: Standard
Diethylcarbamazine is the most satisfactory treatment. Surgical removal of
large adult worms may be necessary. Mild cases may be left untreated. Please
see article on Filariasis for further information.
Therapies: Investigational
This disease entry is based upon medical information available through
September 1989. Since NORD's resources are limited, it is not possible to
keep every entry in the Rare Disease Database completely current and
accurate. Please check with the agencies listed in the Resources section for
the most current information about this disorder.
Resources
For more information on Acanthocheilonemiasis, please contact:
National Organization for Rare Disorders (NORD)
P.O. Box 8923
New Fairfield, CT 06812-1783
(203) 746-6518
NIH/National Institute of Allergy and Infectious Diseases
9000 Rockville Pike
Bethesda, MD 20892
(301) 396-5717
Centers for Disease Control (CDC)
1600 Clifton Road, NE
Atlanta, GA 30333
(404) 639-3534
References
Diethylcarbamazine and new compounds for the treatment of filariasis. ADV
PHARMACOL CHEMOTHER (1979) 16:129:94.