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M94A0092.TXT
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1994-10-01
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Document 0092
DOCN M94A0092
TI Hepatitis C virus infection in a sexually active inner city population.
The potential for heterosexual transmission.
DT 9412
AU Daikos GL; Lai S; Fischl MA; Dept. of Medicine, University of Miami
School of Medicine,; Florida 33101.
SO Infection. 1994 Mar-Apr;22(2):72-6. Unique Identifier : AIDSLINE
MED/94350509
AB The prevalence of hepatitis C virus (HCV) infection and associated risk
factors in an inner city sexually active heterosexual population
participating in a prospective study for the evaluation of heterosexual
transmission of human immunodeficiency virus type-1 (HIV-1) were
examined. Individuals with prior history of injection drug use or
receipt of blood products were excluded from the study. Of 571
participants, 25 (4.4%) were seropositive for HCV, 39 (7%) for HIV, and
125 (22%) for hepatitis B virus (HBV). Multivariate analysis revealed
that those with more than ten heterosexual partners in the past 5 years
(OR = 3.7; 95% CI = 1.3, 10.2; P = 0.01), engaging in sexual practices
more than once per week (OR = 3.3; 95% CI = 1.1, 10.1; P = 0.04), with
antibody to hepatitis B core (HBc) antigen (OR = 2.9; 95% CI = 1.1, 7.4;
P = 0.03), and antibody to HIV-1 (OR = 5.8; 95% CI = 1.9; 17.6; P =
0.002) were independently associated with HCV infection. These findings
suggest that heterosexual transmission of HCV may occur in an inner city
sexually active heterosexual population.
DE Adolescence Adult Aged Female Florida/EPIDEMIOLOGY Hepatitis
B/COMPLICATIONS/*EPIDEMIOLOGY/TRANSMISSION Hepatitis
C/COMPLICATIONS/*EPIDEMIOLOGY/*TRANSMISSION Human HIV
Infections/COMPLICATIONS/*EPIDEMIOLOGY/TRANSMISSION *HIV-1 Male
Middle Age Multivariate Analysis Odds Ratio *Population Surveillance
Prevalence Prospective Studies Risk Factors *Sex Behavior Sexual
Partners Support, U.S. Gov't, P.H.S. *Urban Population JOURNAL
ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).