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M94A0091.TXT
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1994-10-01
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Document 0091
DOCN M94A0091
TI Mucocutaneous diseases in drug addicts with or without HIV infection. A
case-control study.
DT 9412
AU Gaeta GB; Maisto A; Sichenze C; Satriano RA; Sardaro C; Giusti G;
Clinica Malattie Infettive, Seconda Universita, Naples, Italy.
SO Infection. 1994 Mar-Apr;22(2):77-80. Unique Identifier : AIDSLINE
MED/94350510
AB A case-control study was performed to evaluate the prevalence of
mucocutaneous diseases in 106 male drug addicts (age 21-38 years) with
or without HIV infection. A mucocutaneous disease was recorded in ten
out of 64 HIV-negative and in 20 of 42 HIV-positive patients (OR = 4.9;
p < 0.01). Some mucocutaneous diseases were present in similar
proportions in both groups (i.e. fungal skin lesions), while others were
typically present only in HIV-positive patients. Stratification for
possible confounding factors, such as years of drug addiction and number
of sexual partners, confirmed that HIV infection is the main risk factor
for mucocutaneous disease. Stratification according to the number of
CD4-positive cells showed that the more advanced the HIV disease, the
more frequently mucocutaneous disease was present (p = 0.02). The study
demonstrates that many, but not all, mucocutaneous diseases are
associated with HIV infection.
DE Adult Case-Control Studies Confounding Factors (Epidemiology) Human
HIV Infections/COMPLICATIONS/*EPIDEMIOLOGY Male Mucous Membrane Odds
Ratio *Population Surveillance Prevalence Risk Factors Sexual
Partners Skin Diseases/COMPLICATIONS/*EPIDEMIOLOGY Substance
Dependence/*COMPLICATIONS Support, Non-U.S. Gov't JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).