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Document 0078
DOCN M94A0078
TI Improved body weight status as a result of nutrition intervention in
adult, HIV-positive outpatients.
DT 9412
AU McKinley MJ; Goodman-Block J; Lesser ML; Salbe AD; Center for Special
Studies, New York Hospital, NY.
SO J Am Diet Assoc. 1994 Sep;94(9):1014-7. Unique Identifier : AIDSLINE
MED/94351121
AB OBJECTIVE: Malnutrition is an important consequence of infection with
the human immunodeficiency virus (HIV); involuntary weight loss greater
than 10% is one criterion that the Centers for Disease Control and
Prevention uses for the diagnosis of acquired immunodeficiency syndrome
(AIDS). This study was designed to determine whether nutrition
intervention in a group of adult, HIV-positive outpatients affected
weight maintenance. METHODS: We undertook a retrospective review of 175
patient charts from the AIDS Reproductive Health Clinic and the Center
for Special Studies at The New York Hospital. Forty-nine charts were
excluded because the patient expressed a desire to reduce weight,
discontinued medical care, or died. Seven charts were eliminated because
of missing data. In the remaining patients (n = 119), weights were
recorded for the initial clinic contact and for a follow-up visit at
least 6 months later. Nutrition intervention completed by a registered
dietitian was indicated on 42 patient charts (intervention group);
intervention included dietary assessment, intake analysis, appropriate
counselling, follow-up, and provision of supplements as needed. The
remaining 77 charts did not indicate nutrition intervention; this group
was called the nonintervention group. Differences between the
intervention and nonintervention groups were analyzed using the
two-tailed Fisher exact test and the Mann-Whitney nonparametric test.
RESULTS: Forty-two subjects (35% of the total) recieved nutrition
intervention, including all of those with gastrointestinal problems (n =
10) and wasting (n = 11). Individuals in the intervention group gained a
significant (P < .02) 1.2 +/- 11.4 lb (mean +/- standard deviation;
median = +3 lb) compared with those in the nonintervention group who
lost a mean of 3.5 +/- 12.8 lb (median = -4 lb). Twenty-six subjects
(63%) in the intervention group maintained or gained weight compared
with 32 subjects (42%), in the nonintervention group. CONCLUSION: The
results of this study suggest that nutrition intervention in
HIV-infected persons can improve nutritional status and may lead to an
enhanced ability to fight infection.
DE Adult *Body Weight Emaciation/COMPLICATIONS Female Follow-Up Studies
Gastrointestinal Diseases/COMPLICATIONS Human HIV
Infections/COMPLICATIONS/*DIET THERAPY Leukocyte Count Male Middle
Age Nutrition Disorders/*PREVENTION & CONTROL Pneumonia, Pneumocystis
carinii/COMPLICATIONS Retrospective Studies Support, U.S. Gov't,
P.H.S. Syndrome T4 Lymphocytes JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).