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Document 0077
DOCN M94A0077
TI Nutrition: a cofactor in HIV disease.
DT 9412
AU Timbo BB; Tollefson L; Center for Food Safety and Applied Nutrition,
Food and Drug; Administration, Washington, DC.
SO J Am Diet Assoc. 1994 Sep;94(9):1018-22. Unique Identifier : AIDSLINE
MED/94351122
AB The relationships among nutritional status, infectious disease, and the
immune system suggest that nutrition may be a cofactor in human
immunodeficiency virus (HIV) progression. We examined nutrition as a
cofactor in HIV disease by reviewing the current literature on the
interactions of nutrition, infectious disease processes, and immune
system dysfunction. Studies demonstrate that poor nutritional status and
infection affect the immune system and interact with each other. This
relationship leads to the development of opportunistic infections and
malignancies, which may result in a diagnosis of acquired
immunodeficiency syndrome. Moreover, evidence from our review indicates
that nutritional status may play a role in HIV disease progression. We
recommend that clinical trials be conducted to evaluate general
malnutrition and the efficacy of supplementation with specific nutrients
at various stages of HIV disease.
DE Human HIV Infections/*ETIOLOGY/IMMUNOLOGY Immune System/*IMMUNOLOGY
Nutrition Disorders/*COMPLICATIONS *Nutritional Status JOURNAL ARTICLE
REVIEW REVIEW, TUTORIAL
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).