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- │ ------Cardiac and Circulatory------ │
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- │ A. Digitalis Preparations │
- │ B. Dipyridamole │
- │ C. Disopyramide │
- │ D. Inderal │
- │ E. Isoxsuprine │
- │ F. Nitrates │
- │ G. Procardia │
- │ H. Sansert │
- │ │
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- DIGITALIS PREPARATIONS
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- BRAND AND GENERIC NAMES (Generic name in capitals)
- Crystodigin Gitaligen
- Crystogin GITALIN
- Digifortis Lanoxicaps
- Digiglusin Lanoxin
- DIGITALIS Natigozine
- DIGITOXIN Novodigoxin
- DIGOXIN Purodigin
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- BASIC INFORMATION
- Habit forming? No
- Prescription needed? Yes
- Available as generic? Yes
- Drug class: Digitalis preparations
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- USES
- Strengthens weak heart-muscle contractions to prevent
- congestive heart failure.
-
- Corrects irregular heartbeat.
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- DOSAGE AND USAGE INFORMATION
- How to take:
- Tablet or capsule--Swallow with liquid. If you can't
- swallow shole, crumble tablet or open capsule and take
- with liquid or food.
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- Liquid--Dilute dose in beverage before swallowing.
-
- When to take:
- At the same time each day.
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- If you forget a dose:
- Take as soon as you remember up to 12 hours late. If
- more than 12 hours, wait for next scheduled dose (don't
- double this dose).
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- What drug does:
- Strengthens heart-muscle contraction.
- Delays nerve impulses to heart.
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- Time lapse before drug works:
- May require regular use for a week or more.
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- Don't take with:
- Non-prescription drugs without consulting doctor.
- See interaction column and consult doctor.
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- POSSIBLE ADVERSE REACTIONS OR SIDE EFFECTS
- Symptoms What To Do
- Life-threatening:
- None expected
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- Common:
- Appetite loss, diarrhea Continue. Call doctor
- when convenient.
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- Infrequent:
- Drowsiness, lethargy, Discontinue. Call doctor
- disorientation. right away.
-
- Rare:
- Rash, hives Discontinue. Call doctor
- right away.
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- Double or yellow- Continue. Call doctor
- green vision; when convenient.
- enlarged, sensitive
- male breasts;
- tiredness; weakness.
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- OVERDOSE
- Symptoms:
- Nausea, vomiting, diarrhea, vision disturbances with
- halos around lights, irregular heartbeat, confusion,
- hallucinations, convulsions.
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- What to do:
- Dial 0 (operator) or 911 (emergency) for an ambulance or
- medical help. Then give first aid immediately.
-
- See emergency information.
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- WARNINGS AND PRECAUTIONS
- Don't take if:
- You are allergic to any digitalis preparation.
- Your heartbeat is slower than 50 beats per minute.
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- Before you start, consult your doctor:
- If you have taken another digitalis preparation in past
- 2 weeks.
-
- If you have taken a diuretic within 2 weeks.
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- If you have liver or kidney disease.
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- If you have a thyroid disorder.
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- If you will have surgery within 2 months, including
- dental surgery, requiring general of spinal anesthesia.
-
- Over age 60:
- Adverse reactions and side effects may be more frequent
- and severe than in younger persons.
-
- Pregnancy:
- Studies inconclusive on harm to unborn child. Consult
- your doctor.
-
- Breast-feeding:
- Drug filters into milk. May harm child. Avoid.
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- Infants and children:
- Use only under medical supervision.
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- Prolonged use:
- No problems expected.
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- Skin and sunlight:
- No problems expected.
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- Driving, piloting or hazardous work:
- Possible vision disturbances. Otherwise, no problems
- expected.
-
- Discontinuing:
- Don't stop without doctor's advice.
-
- Others:
- No problems expected.
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- POSSIBLE INTERACTION WITH OTHER DRUGS
- Generic Name or Class of Drugs Combined Effect
- Albuterol Increased risk of
- heartbeat irregularity.
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- Amiodarone Increased digitalis
- effect.
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- Antacids Decreased digitalis
- effect.
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- Anticonvilsants Increased digitalis
- (hydantoin) effect at first, then
- decreased.
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- Beta-adrenergic blockers Increased digitalis
- effect.
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- Calcium supplements Decreased digitalis
- effect.
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- Cortisone drugs Digitalis toxicity.
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- Diuretics Possible digitalis
- toxicity.
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- Ephedrine Disturbed heart rhythm.
- Avoid.
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- Epinephrine Disturbed heart rhythm.
- Avoid.
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- Flecainide May increase digitalis
- blood level.
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- Guanethidine Increased digitalis
- effect.
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- Indapamide Excessive potassium loss
- that may cause irregular
- heartbeat.
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- Laxatives Decreased digitalis
- effect.
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- Oxyphenbutazone Decreased digitalis
- effect.
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- Phenobarbital Decreased digitalis
- effect.
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- Phenylbutazone Decreased digitalis
- effect.
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- Potassium supplements Overdosage of either
- drug may cause severe
- heartbeat irregularity.
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- Quinidine Increased digitalis
- effect.
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- Rauwolfia alkaloids Increased digitalis
- effect.
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- Thyroid hormones Digitalis toxicity.
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- POSSIBLE INTERACTION WITH OTHER SUBSTANCES
- Interacts With Combined Effect
- Alcohol None expected.
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- Beverages
- Caffeine drinks. Irregular heartbeat.
- Avoid.
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- Cocaine Irregular heartbeat.
- Avoid.
-
- Foods None expected.
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- Marijuana Decreased digitalis
- effect.
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- Tobacco Irregular heartbeat.
- Avoid.
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- DIPYRIDAMOLE
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- BRAND NAMES
- Apo-Dipyridamole Pyridamole
- Persantine SK-Dipyridamole
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- BASIC INFORMATION
- Habit forming? No
- Prescription needed? U.S.: yes - Canada: No
- Available as generic? Yes
- Drug class: Coronary vasodilator
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- USES
- Reduces frequency and intensity of angina attacks.
- Prevents blood clots after heart surgery.
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- DOSAGE AND USAGE INFORMATION
- How to take:
- Tablet or capsule - swallow with liquid. If you can't
- swallow whole, crumble tablet or open capsule and take
- with liquid.
-
- When to take:
- 1 hour before meals.
-
- If you forget a dose:
- Take as soon as you remember up to 2 hours late. If
- more than 2 hours, wait for next scheduled dose (don't
- double this dose).
-
- What drug does:
- Probably dilates blood vessels to increase oxygen to
- heart.
- Prevents platelet clumping, which causes blood clots.
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- Time lapse before drug works:
- 3 months of continual use.
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- POSSIBLE ADVERSE REACTIONS OR SIDE EFFECTS
- Symptoms What to do
- Life-threatening:
- None expected.
-
- Common:
- None expected.
-
- Infrequent:
- * Dizziness, fainting, Discontinue. Call doctor
- headache. right away.
- *Red flush, rash, Continue. Call doctor
- nausea, vomiting, when convenient.
- cramps, weakness.
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- Rare:
- None expected.
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- OVERDOSE
- Symptoms:
- Decreased blood pressure; weak, rapid pulse; cold,
- clammy skin; collapse.
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- What to do:
- *Dial 0 (operator) or 911 (emergency) for an ambulance
- or medical help. Then give first aid immediately.
- *If patient is unconscious and not breathing, give
- mouth-to-mouth breathing. If there is no heartbeat, use
- cardiac massage and mouth-to-mouth breathing (CPR).
- Don't try to make patient vomit. If you can't get help
- quickly, take patient to nearest emergency facility.
- *See emergency information.
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- WARNINGS AND PRECAUTIONS
- Don't take if:
- You are allergic to dipyridamole.
- You are recovering from a heart attack.
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- Before you start, consult your doctor:
- If you have low blood pressure.
- If you have liver disease.
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- Over age 60:
- Begin treatment with small doses.
-
- Pregnancy:
- No proven harm to unborn child. Avoid if possible.
-
- Breast-feeding:
- No proven problems. Consult doctor.
-
- Infants and children:
- Not recommended.
-
- Prolonged use:
- No problems expected.
-
- Skin and sunlight:
- No problems expected.
-
- Driving, piloting or hazardous work:
- Avoid if you feel dizzy. Otherwise, no problems
- expected.
-
- Discontinuing:
- Don't discontinue without doctor's advice until you
- complete prescribed dose, even though symptoms diminish
- or disappear.
-
- Others:
- Drug increases your ability to be active without angina
- pain. Avoid excessive physical exertion that might
- injure heart.
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- POSSIBLE INTERACTION WITH OTHER DRUGS
- Generic Name or Drug Class Combined Effect
- Anticoagulants (oral) Increased anticoagulant
- effect. Bleeding
- tendency.
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- Antihypertensives Increased
- antihypertensive effect.
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- Aspirin Increased dipyridamole
- effect. Dose may need
- adjustment.
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- POSSIBLE INTERACTION WITH OTHER SUBSTANCES
- Interacts With Combined Effect
- Alcohol May lower blood pressure
- excessively.
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- Beverages: None expected.
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- Cocaine No proven problems.
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- Foods Decreased dipyridamole
- absorption unless taken
- 1 hour before eating.
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- Marijuana Daily use--Decreased
- dipyridamole effect.
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- Tobacco May decrease dipyridamole
- Nicotine effect.
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