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- Newsgroups: bionet.jobs
- Path: sparky!uunet!news.univie.ac.at!vm.univie.ac.at!A5161DAA
- From: A5161DAA@vm.univie.ac.at (Dieter Blaas)
- Subject: POST DOC WANTED
- Message-ID: <1992Nov19.091305.2587@newssrv.edvz.univie.ac.at>
- Sender: news@newssrv.edvz.univie.ac.at (News System - Vienna University)
- Nntp-Posting-Host: helios.edvz.univie.ac.at
- Organization: University of Vienna
- Date: Thu, 19 Nov 1992 09:11:13 GMT
- Lines: 75
-
- CALL FOR POST-DOCS
-
- Vienna, 19th November, 1992.
-
- The Institute of Biochemistry, University of Vienna has recently
- moved into a new building; it is now part of the Vienna Biocenter,
- which includes four other University Departments and is situated next
- to the Institute of Molecular Pathology. The acute problems of lack of
- space and equipment are now a thing of the past and we are enjoying
- the advantages of well-designed laboratories.
- We are in the process of trying to increase the international
- atmosphere of the Institute by attracting Post-Docs from other
- countries. As the University did not provide us with new posts for the
- new building, we cannot offer anything specific. We can, however, offer
- anyone interested in joining our lab our help and support in obtaining
- an EMBO fellowship or a Lise Meitner Stipend (a Stipend from the
- Austrian Government to enable foreign scientists to work in Austria).
- The research interests of our group center on various aspects
- of the interaction of picornaviruses with the host cell, in particular on
- the expression, purification and characterisation of rhinoviral
- proteinase mutants, the nature of viral targets involved in modifying
- the translation machinery of the cell, antibody engineering of
- rhinovirus neutralising antibodies (in collaboration with a
- crystallography group in Barcelona), the expression of other viral
- proteins and the molecular cloning of the equine rhinovirus genome.
- A list of recent publications is enclosed.
- We would hope that anyone interested would have a strong
- background in molecular biology or protein chemistry; if desired, the
- project could be arranged to allow the post-doc to gain experience in
- a particular area.
-
- Contact: Prof. Dr. Ernst Kuechler, or Dr. Tim Skern, or Dr. Dieter Blaas
- Institut fuer Biochemie der Medizinischen Fakultaet
- der Universitaet Wien
- DR. BOHR-GASSE 9, 3. STOCK, A-1030 WIEN, AUSTRIA
- TEL. : (+43) -1/79 515-3125 FAX: (+43)-1/79 515-3114
- E-MAIL : A5161DAA@VM.UNIVIE.AC.AT
-
- Literature:
-
- Gruenberger, M., Pevear, D., Diana, G.D., Kuechler, E., and Blaas,
- D. (1991). Stabilization of human rhinovirus serotype 2 against
- pH induced conformational change by antiviral compounds. J.
- Gen. Virol. 72, 431-433.
-
- Skern, T., Sommergruber, W., Auer, H., Volkmann, P., Zorn, M.,
- Liebig, H-D., Fessl, F., Blaas, D., and Kuechler, E. (1991).
- Substrate requirements of a human rhinovirus 2A proteinase.
- Virology 181, 46-54.
-
- Skern. T., Torgersen, H., Auer, H., Kuechler, E., and Blaas, D.
- (1991). Human rhinovirus mutants stable at low pH. Virology 183,
- 757-763.
-
-
- Liebig, H-D, Skern, T., Luderer, M., Sommergruber, W., Blaas, D.,
- and Kuechler, E. (1991). Proteinase trapping: Screening for viral
- proteinase mutants using *-complementation. Proc. Natl. Acad.
- Sci. U.S.A. 88, 5979 - 5983.
-
- Hofer, F., Berger, B., Gruenberger, M., Machat, H., Dernick, R.,
- Kuechler, E., and Blaas, D. (1992). Shedding of a rhinovirus
- minor group binding protein: Evidence for a Ca++-dependent
- process. J. Gen. Virol.73, 627 - 632.
-
- Tormo, J., Stadler, E., Skern, T., Auer, H., Kanzler, O., Betzel, C.,
- Blaas, D., and Fita, I. (1992). Three dimensional structure of the
- Fab fragment of a neutralizing antibody to human rhinovirus
- serotype 2. Protein Science 1, 1154 - 1161.
-
- Sommergruber, W., Ahorn, H., Zophel, A., Maurer-Fogy, I., Fessl, F.,
- Schnorrenberg, G., Liebig, H-D., Blaas, D., Kuechler, E., and
- Skern, T. (1992). Cleavage Specificity on Synthetic Peptide
- Substrates of Human Rhinovirus 2 Proteinase 2A. J. Biol. Chem.
- (in press).
-