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- From: Billi Goldberg <bigoldberg@igc.org>
- Subject: Houston Post Article dated 7/17/92
- Message-ID: <1992Jul21.211052.18625@cs.ucla.edu>
- Note: non-commercial reproduction.
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- Archive-Number: 5739
- Organization: UCLA, Computer Science Department
- Date: Mon, 20 Jul 92 16:36:52 PDT
- Approved: ddodell@stjhmc.fidonet.org (David Dodell)
- Lines: 91
-
- The following information has been summarized and excerpted from the
- Friday, July 17, 1992, edition of The Houston Post with the permission
- of the authors, Tom Curtis and Patricia Manson.
-
- This article is not copyrighted.
-
- ************************************************************************
- SCIENTISTS URGE SCREENING OF POLIO VACCINE FOR HIV
-
- A controversial theory that AIDS may have been spawned by a polio
- vaccine tested in Africa more than 30 years ago finally seems to be
- headed for scientific analysis.
-
- A co-chairman of a committee of scientists said Thursday it will
- recommend testing samples of a polio vaccine found at The Wistar
- Institute of Anatomy and Biology in Philadelphia. They would be
- screened for the virus believed to cause AIDS, as well as for precursor
- viruses.
-
- "Basically we think we should leave no stone unturned" in examining the
- theory that the possibly contaminated vaccine somehow introduced AIDS
- into humans, said Dr. Claudio Basilico, a co-chairman of the committee.
-
- Basilico said it still was not clear which, if any, of the samples found
- in freezers at the Wistar were from the tests conduction in Africa.
-
- The five-member committee was appointed in March by Wistar, whose former
- director developed a poliovirus vaccine that was tested on about 325,000
- people in central equatorial Africa from 1957 to 1960.
-
- That region of Africa is among the areas with the highest percentages of
- people who test positive for the AIDS virus, and where many scientists
- believe AIDS entered the human population.
-
- The vaccines were weakened polio viruses grown in a medium--primary
- monkey kidney tissue--from monkey species now known to be susceptible to
- infection with a number of viruses.
-
- These viruses include lentiviruses, the subfamily of viruses containing
- the human immunodeficiency virus (HIV) believed to cause AIDS. Those
- viruses also include simian immunodeficiency virus (SIV), a retrovirus
- cousin of the HIV. Some scientists now speculate that SIV and HIV may
- be the same virus.
-
- In March, workers began combing through Wistar's biological freezers and
- freezer rooms in a search for specimens of the Congo vaccine. About the
- same time, Wistar officials appointed the committee of scientists to
- look at the theory linking the vaccine to the origin of AIDS in humans.
-
- However, in a May press release, Wistar officials described the idea as
- "a highly speculative theory." And Thursday, Basilico--like many others
- in the medical establishment--also discounted the theory, saying the
- committee thinks "the probability of this even occurring is extremely
- unlikely."
-
- Basilico also played down the implications of the theory, even if it is
- proved to be true.
-
- "It's really an interesting possibility, but if it is true, what will it
- do to help us fight AIDS?...the present epidemic is not going to be
- solved by this," said Basilico, chairman of the Department of
- Microbiology at New York University School of Medicine.
-
- But he said the final decision on whether to act on the committee's
- recommendations will rest with Wistar, the oldest private, nonprofit
- biomedical research and training institute in the nation.
-
- Wistar officials were not available for comment Thursday.
-
- Basilico made his comments Thursday afternoon after four of the five
- committee members met at New York University. The committee will issue
- a final report by Sept. 15, he said.
-
- Many details of the committee's recommendation that polio vaccine
- samples be tested remain to be worked out, Basilico said.
-
- "In all frankness, it may not be all that easy to find people to do this
- testing because it's a lot of work," he said. He said it probably would
- be too expensive to test all of the samples found, which number "no more
- than 100."
-
- At least one scientist is eager to do the work and said he would perform
- it for free.
-
- Robert C. Bohannon said he was prepared to test at least 100 samples for
- numerous viruses, including HIV.
-
- Bohannon is director of research for Onasco Companies Inc., a maker of
- vaccines and diagnostic kits for AIDS and AIDS-like viruses.
- ************************************************************************
-
-