c't freeware shareware 2001 January/CT_SW0101.ISO/pc/software/office/datenbk/bgbasic.exe/_SETUP.1/Medline_Pubmed_Sample.txt

Text File | 2001-03-22 | 17KB | 406 lines

UI  - 20582881
PMID- 11149990
DA  - 20010122
DCOM- 20010208
IS  - 0091-6749
VI  - 107
IP  - 1
DP  - 2001 Jan
TI  - House dust mite and cockroach exposure are strong risk factors for
      positive allergy skin test responses in the Childhood Asthma Management
      Program.
PG  - 48-54
AB  - BACKGROUND: Children with asthma have a high prevalence of environmental
      allergies, especially to indoor allergens. The relationships of exposure
      to indoor allergens (dust mites, cat, dog, cockroach, and molds) and other
      host factors to allergy sensitization have not been evaluated
      simultaneously in a large cohort. OBJECTIVES: We studied 1041 children
      aged 5 to 12 years with mild-to-moderate asthma to determine risk factors
      associated with having positive allergy skin test responses to indoor
      allergens. Also, we described, compared, and contrasted 6 allergens in the
      home environments of these children from 8 North American cities. METHODS:
      Data were used from baseline visits of the Childhood Asthma Management
      Program. Patients' sensitivities to house dust mites (Dermatophagoides
      farinae and Dermatophagoides pteronyssinus), cats, dogs, cockroaches, and
      molds were examined for relationships to demographic variables, home dust
      allergen exposures, number of other positive allergy skin test responses,
      total serum IgE levels, and smoking in the home. RESULTS: San Diego
      (78.5%) and Toronto (59.3%) had the topmost percentages of homes with
      moderate-to-high house dust mite levels. Boston (21.5%), St Louis (16.3%),
      and Baltimore (13.4%) had the highest percentages of homes with detectable
      levels of cockroach allergen. For house dust mites, the higher the level
      of allergen exposure, the more likely patients were to have positive
      allergy skin test responses, with relative odds of 9.0 (95% confidence
      interval, 5.4-15.1) for those exposed to high mite levels (>10.0 microg/g
      dust) relative to those unexposed. Even exposure to low levels of mite
      allergen (0.020-2.0 &mgr;g/g) was found to be a significant risk factor
      for sensitization. For cockroach allergen, those with detectable home
      exposure were more likely to have positive skin test responses (relative
      odds, 2.2; 95% confidence interval, 1.3-3.8) than those with undetectable
      exposure. In contrast, levels of exposure to cat, dog, and mold allergens
      were not related to sensitization rates. For cat allergen, this may
      reflect lower rates of cat ownership among highly sensitized subjects.
      Furthermore, the number of allergy skin test responses that were positive,
      excluding the test for the outcome of interest for each model, and total
      serum IgE levels were strong independent predictors of sensitization.
      CONCLUSIONS: Levels of exposure determined by house dust analysis are
      important determinants of sensitization for dust mite and cockroach
      allergen. This relationship was not demonstrable for cat, dog, or mold
      allergens, possibly because of confounding factors. For all allergens
      studied, the degree of atopy, determined by the total number of positive
      skin test responses or by total serum IgE levels, is an important
      contributing risk factor for sensitization.
AD  - Johns Hopkins Asthma and Allergy Center, Baltimore, MD, USA.
AU  - Huss K
AU  - Adkinson NF
AU  - Eggleston PA
AU  - Dawson C
AU  - Van Natta ML
AU  - Hamilton RG
LA  - eng
PT  - Journal Article
CY  - UNITED STATES
TA  - J Allergy Clin Immunol
JC  - H53
JID - 1275002
RN  - 0 (Allergens)
RN  - 37341-29-0 (IgE)
SB  - AIM
SB  - IM
MH  - Air Pollution, Indoor/statistics & numerical data
MH  - Allergens/*analysis
MH  - Animal
MH  - Asthma/diagnosis/epidemiology/*immunology
MH  - Cats/immunology
MH  - Child
MH  - Child, Preschool
MH  - Cockroaches/*immunology
MH  - Cross-Sectional Studies
MH  - Dogs/immunology
MH  - Dose-Response Relationship, Immunologic
MH  - Dust/*analysis
MH  - Female
MH  - Human
MH  - Hypersensitivity, Immediate/immunology
MH  - IgE/blood
MH  - Male
MH  - Mites/*immunology
MH  - Risk Factors
MH  - Skin Tests
EDAT- 2001/1/10 11
MHDA- 2001/3/3 10:1:00
AID - a111146 [pii]
URL - http://www.mosby.com/scripts/om.dll/serve?action=searchDB&searchDBfor=art&
      artType=abs&id=a111146&target=
PST - ppublish
SO  - J Allergy Clin Immunol 2001 Jan;107(1):48-54.




UI  - 20575936
PMID- 11133405
DA  - 20010129
DCOM- 20010208
IS  - 0091-6765
VI  - 108
IP  - 12
DP  - 2000 Dec
TI  - A 4-year-old girl with manifestations of multiple chemical sensitivities.
PG  - 1219-23
AB  - Multiple chemical sensitivities (MCS) syndrome, also known as idiopathic
      environmental intolerance, is a controversial diagnosis that encompasses a
      wide range of waxing and waning, subjective symptoms referable to more
      than one body system and provoked by exposure to low levels of chemicals,
      foods, or other agents in the environment. Although MCS has been studied
      extensively, a unifying mechanism explaining the illness remains obscure,
      and clinicians are divided as to whether such a medical entity exists
      separately from psychosomatic syndromes. MCS is an adult diagnosis; there
      is little reference to pediatric cases in the scientific literature. In
      this case from the Pediatric Environmental Health Subspecialty Unit at
      Boston's Children's Hospital, I present the case of a preschool child who
      had suffered from milk allergy and poor weight gain as an infant, and then
      later developed asthma, allergic symptoms, sinusitis, headaches, fatigue,
      and rashes precipitated by an expanding variety of chemicals, foods, and
      allergens. I review definitions, mechanisms, diagnostic strategies, and
      management, and discuss some uniquely pediatric features of MCS as
      illustrated by this case.
AD  - Pediatric Environmental Health Subspecialty Unit and Clinical Toxicology
      Program, Children's Hospital Boston, MA 02115, USA.
      [e-mail]
AU  - Woolf A
LA  - eng
PT  - Clinical Conference
PT  - Journal Article
CY  - UNITED STATES
TA  - Environ Health Perspect
JC  - EI0
JID - 0330411
SB  - IM
MH  - Adaptation, Psychological
MH  - Case Report
MH  - Child, Preschool
MH  - Diagnosis, Differential
MH  - Diet
MH  - *Environmental Exposure
MH  - Family Health
MH  - Female
MH  - Food Hypersensitivity
MH  - Human
MH  - Multiple Chemical Sensitivity/*diagnosis/physiopathology/therapy
EDAT- 2001/1/3 11
MHDA- 2001/3/3 10:1:00
AID - sc271_5_1835 [pii]
PST - ppublish
SO  - Environ Health Perspect 2000 Dec;108(12):1219-23.




UI  - 20416450
PMID- 10960213
DA  - 20000913
DCOM- 20001030
IS  - 1054-139X
VI  - 27
IP  - 3
DP  - 2000 Sep
TI  - Video intervention/prevention assessment: a patient-centered methodology
      for understanding the adolescent illness experience.
PG  - 155-65
AB  - OBJECTIVE: To better understand the issues and needs of adolescents with
      chronic health conditions, the Video Intervention/Prevention Assessment
      (VIA) integrates video technology with qualitative research methods to
      obtain a patient-centered perspective on illness and health care. METHODS:
      Young people with chronic disease are interviewed for condition-specific
      verbal reports (CSVRs) of their medical and psychosocial histories.
      Standardized health-related quality of life (HRQL) instruments are
      administered. Trained to use video camcorders, participants record visual
      narratives of their illness experiences. They document their daily lives,
      interview families and friends, and record personal monologues regarding
      their observations, behaviors, understandings, and beliefs about their
      disease. On completion of the visual narratives, HRQL is again evaluated.
      Verbal, scaled, and visual data are analyzed from three perspectives:
      medical, psychosocial, and anthropological. Data from the CSVRs, HRQLs,
      and visual narratives are triangulated to validate and enrich findings.
      RESULTS: Investigating the illness experience from the adolescent
      patient's perspective, the VIA method was pilot-tested with children and
      adolescents with asthma. As a research tool, VIA found environmental risk
      factors, medication adherence problems, and outcome-affecting illness
      beliefs and psychological states that were not identified by standard
      clinical tools. As an intervention, VIA showed that it may be an effective
      tool for health-related environmental surveys. Participants'
      condition-specific quality of life showed measurable improvement after the
      self-examination process of VIA. As communication, VIA made apparently
      counterproductive patient behaviors understandable by showing them in
      context with the adolescent's experience of illness and health care. VIA
      can enhance medical history-taking and management strategies, improve
      adolescents' self-management skills, and educate clinicians, families, and
      students of the health care professions about the realities of the
      adolescent living with a chronic health condition.
AD  - Division of Adolescent/Young Adult Medicine, Children's Hospital, Boston,
      Massachusetts 02115, USA.
AU  - Rich M
AU  - Lamola S
AU  - Gordon J
AU  - Chalfen R
LA  - eng
PT  - Journal Article
CY  - UNITED STATES
TA  - J Adolesc Health
JC  - A0J
JID - 9102136
SB  - IM
MH  - Adolescence
MH  - Asthma/etiology/*psychology/rehabilitation
MH  - Boston
MH  - Child
MH  - Chronic Disease/psychology
MH  - Female
MH  - Hospitals, Pediatric
MH  - Hospitals, Urban
MH  - Human
MH  - Informed Consent
MH  - Interviews/*methods
MH  - Male
MH  - Medical History Taking/*methods
MH  - Patient-Centered Care/*methods
MH  - Physician-Patient Relations
MH  - Pilot Projects
MH  - *Quality of Life
MH  - *Sick Role
MH  - Support, Non-U.S. Gov't
MH  - *Video Recording/methods
EDAT- 2000/8/26 11
MHDA- 2001/2/28 10:1:00
AID - S1054139X00001142 [pii]
PST - ppublish
SO  - J Adolesc Health 2000 Sep;27(3):155-65.




UI  - 20358823
PMID- 10891023
DA  - 20000801
DCOM- 20000801
LR  - 20001218
IS  - 1072-4710
VI  - 154
IP  - 7
DP  - 2000 Jul
TI  - Relationship between disease and psychological adaptation in children in
      the Childhood Asthma Management Program and their families. CAMP Research
      Group.
PG  - 706-13
AB  - OBJECTIVE: To test the hypotheses that the burden of childhood asthma
      compromises psychological adaptation and that the degree of compromise
      increases with disease severity. DESIGN: The Childhood Asthma Management
      Program (CAMP) is a multicenter randomized clinical trial initiated and
      funded by the National Heart, Lung, and Blood Institute. SETTING: Study
      sites were located in Albuquerque, NM, Baltimore, Md, Boston, Mass,
      Denver, Colo, St Louis, Mo, San Diego, Calif, Seattle, Wash, and Toronto,
      Ontario. PARTICIPANTS: A total of 1,041 children aged 5 to 12 years were
      randomized to the trial after confirming their mild to moderate asthma.
      MAIN OUTCOME MEASURES: Psychological questionnaires administered at
      baseline to parents and participants assessed anxiety, depression,
      behavioral competence, social support, and family functioning. RESULTS:
      Psychological difficulty was not increased in this group of asthmatic
      children and their families. Psychological adaptation in the children was
      associated with the psychological adaptation of the family but not with
      disease-related variables. Scores from the Impact on Family Scale, a
      measure of family quality of life related to the child's illness, were
      associated more strongly with the overall psychological characteristics of
      the family and child and very little with disease characteristics or
      severity. CONCLUSIONS: Mild to moderate asthma has imposed modest effects
      on the daily life but not the psychological health of this group of
      children. Variation in the psychological characteristics of these children
      was, as is the case for most children, traceable to the overall
      psychological adaptation of their families.
AD  - National Jewish Medical and Research Center, Denver, Colo 80206, USA.
AU  - Bender BG
AU  - Annett RD
AU  - Ikle D
AU  - DuHamel TR
AU  - Rand C
AU  - Strunk RC
LA  - eng
ID  - NO1-HR16044/HR/NHLBI
ID  - NO1-HR16045/HR/NHLBI
ID  - NO1-HR16046/HR/NHLBI
ID  - et al.
PT  - Journal Article
CY  - UNITED STATES
TA  - Arch Pediatr Adolesc Med
JC  - BWF
JID - 9422751
SB  - AIM
SB  - IM
MH  - *Adaptation, Psychological
MH  - Asthma/*psychology/rehabilitation
MH  - Child
MH  - Child, Preschool
MH  - Cost of Illness
MH  - Family/*psychology
MH  - Female
MH  - Human
MH  - Male
MH  - Parent-Child Relations
MH  - Personality Assessment
MH  - *Sick Role
MH  - Support, U.S. Gov't, P.H.S.
EDAT- 2000/07/13 11
MHDA- 2000/08/06 11
AID - poa90439 [pii]
PST - ppublish
SO  - Arch Pediatr Adolesc Med 2000 Jul;154(7):706-13.




UI  - 20306675
PMID- 10850502
DA  - 20000621
DCOM- 20000621
LR  - 20001218
IS  - 1072-4710
VI  - 154
IP  - 6
DP  - 2000 Jun
TI  - Comparing asthma care for Medicaid and non-Medicaid children in a health
      maintenance organization.
PG  - 563-8
AB  - OBJECTIVE: To compare ambulatory visit patterns, rates of medication use,
      and emergency department and hospital utilization for children with asthma
      covered under Medicaid and commercial payers within the same health
      maintenance organization (HMO). DESIGN: Retrospective cohort study.
      SETTING: Eleven staff-model pediatric departments of an HMO. PATIENTS: A
      total of 1928 Medicaid and 11007 non-Medicaid children aged 2 to 18 years
      with at least 1 encounter with a diagnosis of asthma between October 1,
      1991, and September 30, 1996. METHODS: We linked patient-level data from
      the HMO's automated medical record system for ambulatory encounters, a
      claims system for emergency department and hospital care, and an automated
      pharmacy dispensing database. Medicaid and non-Medicaid patients were
      compared for all encounter types and for prescribing and dispensing of
      beta-agonist and controller medications (inhaled corticosteroids and
      cromolyn sodium). Incidence rate ratios were calculated from Poisson
      regression models to control for age, sex, and, when appropriate,
      beta-agonist dispensing rate. The number of refills authorized on each
      prescription and the fraction of medications dispensed as refills compared
      with new prescriptions were compared for Medicaid and non-Medicaid
      patients. RESULTS: Medicaid-insured children in the HMO were 1.4 times
      (95% confidence interval, 1.2-1.5) more likely to receive care in
      emergency departments and 1.3 times (95% confidence interval, 1.1-1.5)
      more likely to be hospitalized for their asthma compared with non-Medicaid
      members. Medicaid and non-Medicaid enrollees had similar yearly rates of
      nonurgent (1.32 vs 1.17) and urgent (0.38 vs 0.31) ambulatory visits.
      Beta-agonists were dispensed roughly equally to Medicaid and non-Medicaid
      members. Although Medicaid patients were less likely to have controller
      medications dispensed (relative risk, 0.72; 95% confidence interval,
      0.69-0.74), they were equally likely to have them prescribed. CONCLUSIONS:
      Differences in ambulatory contact for Medicaid members do not explain the
      higher rates of emergency department visits and hospitalization in this
      population. Reasons for lower rates of dispensing of controller
      medications should continue to be investigated as one cause of increased
      morbidity for low-income children with asthma.
AD  - Department of Ambulatory Care and Prevention, Harvard Medical School and
      Harvard Pilgrim Health Care, Boston, Mass 02215, USA.
AU  - Finkelstein JA
AU  - Barton MB
AU  - Donahue JG
AU  - Algatt-Bergstrom P
AU  - Markson LE
AU  - Platt R
LA  - eng
PT  - Journal Article
CY  - UNITED STATES
TA  - Arch Pediatr Adolesc Med
JC  - BWF
JID - 9422751
RN  - 0 (Anti-Asthmatic Agents)
SB  - AIM
SB  - IM
MH  - Adolescence
MH  - Anti-Asthmatic Agents/therapeutic use
MH  - Asthma/*drug therapy
MH  - Boston
MH  - Child
MH  - Child, Preschool
MH  - Chronic Disease
MH  - Cohort Studies
MH  - Comparative Study
MH  - Emergencies
MH  - Female
MH  - Health Maintenance Organizations/statistics & numerical data/*utilization
MH  - Human
MH  - Male
MH  - Medicaid/statistics & numerical data/*utilization
MH  - Retrospective Studies
MH  - Support, Non-U.S. Gov't
MH  - United States
EDAT- 2000/06/13 09
MHDA- 2000/06/24 11
PST - ppublish
SO  - Arch Pediatr Adolesc Med 2000 Jun;154(6):563-8.