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- $Unique_ID{BRK04121}
- $Pretitle{}
- $Title{Polymyalgia Rheumatica}
- $Subject{Polymyalgia Rheumatica PMR Senile Rheumatic Gout Anarthritic
- syndrome}
- $Volume{}
- $Log{}
-
- Copyright (C) 1986, 1989 National Organization for Rare Disorders, Inc.
-
- 256:
- Polymyalgia Rheumatica
-
- ** IMPORTANT **
- It is possible the main title of the article (Polymyalgia Rheumatica) is
- not the name you expected. Please check the SYNONYMS listing to find the
- alternate names and disorder subdivisions covered by this article.
-
- Synonyms
-
- PMR
- Senile Rheumatic Gout
- Anarthritic syndrome
-
- General Discussion
-
- ** REMINDER **
- The information contained in the Rare Disease Database is provided for
- educational purposes only. It should not be used for diagnostic or treatment
- purposes. If you wish to obtain more information about this disorder, please
- contact your personal physician and/or the agencies listed in the "Resources"
- section of this report.
-
-
- Polymyalgia Rheumatica is a disorder characterized by pain and stiffness
- in certain muscle groups without causing permanent weakness or atrophy.
-
- Symptoms
-
- The major symptoms of Polymyalgia Rheumatica (PMR) are pain and stiffness in
- the neck, shoulders, upper arms, low back, hips and thighs. The symptoms
- often come on quickly and the stiffness is most severe in the morning,
- causing difficulty getting out of bed. Difficulty in moving may also occur
- after long periods of sitting still. In some patients onset of the symptoms
- occurs very gradually.
-
- The pain of PMR is felt on both sides of the body. Fever, lack of
- appetite (anorexia), fatigue, weight loss and depression may also be present.
- In spite of the severe pain, examination of the muscles does not show any
- abnormality. A nonhemolytic anemia may be present in some patients.
-
- Causes
-
- The cause of Polymyalgia Rheumatica is not known.
-
- Affected Population
-
- Polymyalgia Rheumatica occurs most commonly in people over 50 years of age.
- Females are affected four times as often as males, and caucasian people are
- affected more frequently than other racial groups.
-
- Related Disorders
-
- Rheumatoid Arthritis is a chronic disorder characterized by nonspecific,
- inflammation of the peripheral joints, potentially resulting in progressive
- destruction of the joints.
-
- Giant Cell Arteritis (Temporal Arteritis; Cranial Arteritis; or
- Granulomatous Arteritis) is a chronic generalized inflammatory disease of the
- branches of the aortic arch (large arteries coming out of the heart). The
- disorder principally affects temporal and occipital arteries, but many
- develop in almost any large artery. The systematic symptoms of Giant Cell
- Arteritis are the same as those of PMR, to which it may be related. (For
- more information, choose "giant Cell Arteritis" and "arthritis" as your
- search terms in the Rare Disease Database.)
-
- Therapies: Standard
-
- The most effective drugs for treating PMR are the corticosteroids.
- Prednisone is most often prescribed. This treatment often results in rapid
- improvement within a few days after which the dosage is lowered and kept at a
- maintenance level for a few months to several years. Potential side effects
- of prednisone such as weight gain, thinning of the bones, depression, high
- blood pressure, cataracts, diabetes, increased risk of infection and, rarely,
- bleeding from the stomach, should be carefully monitored and prevented by
- reducing the dose or discontinuing when possible.
-
- Some patients respond well to treatment with aspirin, which relieves pain
- and reduces inflammation.
-
- Other drugs sometimes used to treat PMR are the nonsteroidal anti-inflammatory
- drugs which are commonly used to treat many types of arthritis. These drugs
- reduce pain and inflammation much like aspirin, but they cause fewer side
- effects in some people.
-
- During any period of pain and stiffness, people with PMR need to avoid
- being either too active or not active enough. Once drug therapy has taken
- effect, activity can be increased.
-
- Therapies: Investigational
-
- This disease entry is based upon medical information available through March
- 1987. Since NORD's resources are limited, it is not possible to keep every
- entry in the Rare Disease Database completely current and accurate. Please
- check with the agencies listed in the Resources section for the most current
- information about this disorder.
-
- Resources
-
- For more information on Polymyalgia Rheumatica, please contact:
-
- National Organization for Rare Disorders (NORD)
- P.O. Box 8923
- New Fairfield, CT 06812-1783
- (203) 746-6518
-
- Arthritis Foundation
- 1314 Spring Street, N.W.
- Atlanta, GA 30309
- (404) 872-7100
-
- The National Arthritis and Musculoskeletal and Skin Diseases Information
- Clearinghouse
- Box AMS
- Bethesda, MD 20892
- (301) 495-4484
-
- References
-
- Polymyalgia Rheumatica (PMR). Wilske: Arthritis Medical Information
- Series (1983).
-
-