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- $Unique_ID{BRK04112}
- $Pretitle{}
- $Title{Pneumonia, Eosinophilic}
- $Subject{Pneumonia Eosinophilic Pulmonary Infiltrates with Eosinophilia
- Syndrome Loffler's Syndrome Allergic Bronchopulmonary Aspergillosis
- Tuberculosis Sarcoidosis}
- $Volume{}
- $Log{}
-
- Copyright (C) 1989 National Organization for Rare Disorders, Inc.
-
- 725:
- Pneumonia, Eosinophilic
-
- ** IMPORTANT **
- It is possible that the main title of the article (Eosinophilic
- Pneumonia) is not the name you expected. Please check the SYNONYM listing to
- find the alternate names and disorder subdivisions covered by this article.
-
- Synonyms
-
- Pulmonary Infiltrates with Eosinophilia Syndrome
- Loffler's Syndrome
- Allergic Bronchopulmonary Aspergillosis
-
- Information on the following diseases can be found in the Related
- Disorders section of this report:
-
- Tuberculosis
- Sarcoidosis
-
- General Discussion
-
- ** REMINDER **
- The information contained in the Rare Disease Database is provided for
- educational purposes only. It should not be used for diagnostic or treatment
- purposes. If you wish to obtain more information about this disorder, please
- contact your personal physician and/or the agencies listed in the "Resources"
- section of this report.
-
- Eosinophilic pneumonia is a disorder characterized by an inflammation of
- the lungs and an abnormal increase in the number of certain white blood cells
- (eosinophils) in the lymph nodes, lungs and blood. This disorder is usually
- associated with allergic conditions and various parasitic infections.
-
- Symptoms
-
- Eosinophilic pneumonia usually has a sudden onset. There may be accompanying
- weight loss and increased pulse rate. Symptoms may also include low-grade
- fever, cough with the possibility of blood in the phlegm, wheezing and
- labored breathing. There may also be chills, sweating, pain in the chest and
- a general feeling of ill health. Children with eosinophilic pneumonia may
- have enlargement of the spleen and liver. The symptoms of eosinophilic
- pneumonia may be mild or severe, depending upon the amount of lung area
- affected. Many patients simultaneously have bronchial asthma.
-
- A specific type of eosinophilic pneumonia called allergic
- bronchopulmonary aspergillosis tends to affect individuals with asthma.
- Those affected usually show a worsening of asthmatic symptoms, and may have a
- low-grade fever and phlegm containing brownish flecks.
-
- Causes
-
- Most of the eosinophilic pneumonias are of unknown cause. Some cases are
- caused by parasites including roundworms and Toxocara larvae. Other cases
- are associated with allergies, particularly to drugs such as penicillin,
- aminosalicylic acid, hydralazine, nitrofurantoin, chlorpropamide, or
- sulfonamide. Fungi such as Aspergillus fumigatus, and chemical sensitizers
- such as nickel carbonyl inhaled as a vapor, may also be possible causes.
-
- Allergic bronchopulmonary aspergillosis occurs as a result of an allergic
- reaction to the fungus Aspergillus fumigatus.
-
- Affected Population
-
- Eosinophilic pneumonia may affect anyone. However, it tends to occur most
- often in young men. One specific form of this disorder, allergic
- bronchopulmonary aspergillosis, occurs in individuals with asthma.
-
- Related Disorders
-
- Symptoms of the following disorders can be similar to those of eosinophilic
- pneumonia. Comparisons may be useful for a differential diagnosis:
-
- Tuberculosis is an acute or chronic bacterial infection found most
- commonly in the lungs. The infection is spread like a cold, mainly through
- airborne droplets breathed into the air by an infected person. Symptoms
- include labored breathing, fever, loss of appetite, weight loss, weakness and
- dry cough occasionally with blood in the phlegm. (For more information on
- this disorder, choose "Tuberculosis " as your search term in the Rare Disease
- Database).
-
- Sarcoidosis is a disorder which affects many body systems. It is
- characterized by small round lesions composed of grainy tissue. Symptoms of
- lung infiltration include cough and difficulty breathing. (For more
- information on this disorder, choose "Sarcoidosis" as your search term in the
- Rare Disease Database).
-
- There are many other types of pneumonia caused by bacteria or virus. In
- general the symptoms of pneumonia are similar to eosinophilic pneumonia, so
- diagnostic tests determine which type a patient has.
-
- Therapies: Standard
-
- Eosinophilic pneumonia may be self-limiting, requiring no treatment.
- However, symptoms may persist or disappear spontaneously and recur
- periodically. If symptoms are severe, corticosteroid drugs such as
- prednisone may be administered. Treatment with diethylcarbamazine has also
- proven to be successful. Those cases which are caused by parasitic worms are
- treated with appropriate antiparasitic drugs.
-
- Therapies: Investigational
-
- This disease entry is based upon medical information available through
- December 1989. Since NORD's resources are limited, it is not possible to
- keep every entry in the Rare Disease Database completely current and
- accurate. Please check with the agencies listed in the Resources section for
- the most current information about this disorder.
-
- Resources
-
- For more information on Eosinophilic Pneumonia, please contact:
-
- National Organization for Rare Disorders (NORD)
- P.O. Box 8923
- New Fairfield, CT 06812-1783
- (203) 746-6518
-
- American Lung Association
- 1740 Broadway
- New York, NY 10019
- (212) 315-8700
-
- NIH/National Institute of Allergy and Infectious Diseases
- 9000 Rockville Pike
- Bethesda, MD 20892
- (301) 496-5717
-
- Centers for Disease Control (CDC)
- 1600 Clifton Road NE
- Atlanta, GA 30333
- (404) 329-3534
-
- References
-
- THE MERCK MANUAL, Volume 1, 14th Ed.: Robert Berkow, M.D., ed.-in-chief;
- Merck Sharp & Dohme Laboratories, 1982. Pp. 689-690.
-
- ACUTE EOSINOPHILIC PNEUMONIA: A HYPERSENSITIVITY PHENOMENON? D.B. Badesch
- et al.; AM REV RESPIR DIS (January, 1989; issue 139(1): Pp. 249-252.)
-
- CERBROSPINAL FLUID EOSINOPHILIA AND STERILE SHUNT MALFUNCTION. V.C.
- Traynelis et al.; NEUROSURGERY (November, 1988; issue 23(5): Pp. 645-649.)
-
-