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03147.txt
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1994-01-17
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$Unique_ID{BRK03147}
$Pretitle{}
$Title{erythromycin}
$Subject{E.E.S 200 400 Abbott E-Mycin Boots Eramycin Wesley Eryc Parke-Davis
EryPed Abbott Ery-Tab Erythrocin Stearate Filmtabs Erythromycin Base Ilosone
Dista Pulvules PCE Dispertab Robimycin Wyamycin S Robins Wyeth Antibiotic
erythromycin bacterial infections, infections middle ear respiratory tract
allergic penicillin protein}
$Volume{}
$Log{
E-Mycin*0314701.scf
Eryc*0314702.scf
Erythrocin Stearate Filmtabs*0314703.scf
Ilosone Pulvules*0314704.scf}
Copyright (C) 1993 Publications International, Ltd.
erythromycin
------------------------------------------------------------------------------
BRAND NAMES (Manufacturers)
E.E.S. 200 (Abbott)
E.E.S. 400 (Abbott)
E-Mycin (Boots)
Eramycin (Wesley)
Eryc (Parke-Davis)
EryPed (Abbott)
Ery-Tab (Abbott)
Erythrocin Stearate Filmtabs (Abbott)
Erythromycin Base (Abbott)
Ilosone (Dista)
Ilosone Pulvules (Dista)
PCE Dispertab (Abbott)
Robimycin (Robins)
Wyamycin S (Wyeth)
TYPE OF DRUG
Antibiotic
INGREDIENT
erythromycin
DOSAGE FORMS
Tablets (250 mg, 333 mg, and 500 mg)
Chewable tablets (200 mg)
Enteric-coated tablets (250 mg, 333 mg, and 500 mg)
Film-coated tablets (250 mg, 400 mg, and 500 mg)
Polymer-coated tablets (333 mg)
Capsules (250 mg)
Oral drops (100 mg per 2.5 ml)
Oral suspension (125 mg, 200 mg, 250 mg, and 400 mg per 5-ml spoonful)
STORAGE
Erythromycin tablets and capsules should be stored at room temperature in
tightly closed, light-resistant containers. Erythromycin oral drops and oral
suspension should be stored in the refrigerator in tightly closed,
light-resistant containers. Any unused portion of the liquid forms should be
discarded after 14 days. Erythromycin ethylsuccinate liquid does not need to
be refrigerated; however, refrigeration helps to preserve the taste. This
medication should never be frozen.
USES
Erythromycin is used to treat a wide variety of bacterial infections,
including infections of the middle ear and the respiratory tract. It is also
used to treat infections in persons who are allergic to penicillin. It acts
by preventing the bacteria from manufacturing protein, which prevents their
growth. It is not effective against viruses, parasites, or fungi.
TREATMENT
In order to prevent stomach upset, erythromycin coated tablets and
erythromycin estolate or ethylsuccinate can be taken with food or milk. Other
erythromycin products should be taken with a full glass of water, preferably
on an empty stomach, one hour before or two hours after a meal.
The liquid forms should be taken undiluted.
Each dose of the oral drops should be measured carefully with the dropper
provided.
The oral suspension form of this medication should be shaken well just
before measuring each dose. The contents tend to settle on the bottom of the
bottle, so it is necessary to shake the container to distribute the
ingredients evenly and equalize the doses. Each dose should then be measured
carefully with a specially designed 5-ml measuring spoon. An ordinary kitchen
teaspoon is not accurate enough.
In order to prevent gastrointestinal side effects, the coated tablets and
capsules should be swallowed whole; do not break, chew, or crush these
products.
Erythromycin works best when the level of medicine in your bloodstream is
kept constant. It is best, therefore, to take the doses at evenly spaced
intervals day and night. For example, if you are to take four doses a day,
the doses should be spaced six hours apart.
If you miss a dose of this medication, take the missed dose immediately.
However, if you do not remember to take the missed dose until it is almost
time for your next dose, take it; space the following dose about halfway
through the regular interval between doses; then return to your regular
schedule. Try not to skip any doses.
It is important to continue to take this medication for the entire time
prescribed by your doctor (usually seven to 14 days), even if the symptoms
disappear before the end of that period. If you stop taking this drug too
soon, resistant bacteria continue growing, and the infection could recur.
SIDE EFFECTS
Minor.
Abdominal cramps, diarrhea, fatigue, irritation of the mouth, loss of
appetite, nausea, sore tongue, or vomiting. These side effects should
disappear as your body adjusts to the medication.
Major.
Tell your doctor about any side effects that are persistent or
particularly bothersome. IT IS ESPECIALLY IMPORTANT TO TELL YOUR DOCTOR about
fever, hearing loss, hives, rash, rectal or vaginal itching, or yellowing of
the eyes or skin. Also, if your symptoms of infection seem to be getting
worse rather than improving, you should contact your doctor.
INTERACTIONS
1. Erythromycin can decrease the elimination of aminophylline,
oxtriphylline, theophylline, digoxin, oral anticoagulants (blood thinners,
such as warfarin), and carbamazepine from the body, which can lead to serious
side effects.
2. Therapy with erythromycin may increase the effects of
methylprednisolone.
BE SURE TO TELL YOUR DOCTOR about any medications you are currently
taking, especially any listed above.
WARNINGS
* Tell your doctor about unusual or allergic reactions you have had to
any medications, especially to erythromycin.
* Be sure to tell your doctor if you have ever had liver disease.
* This drug has been prescribed for your current infection only. Another
infection later on, or one that someone else has, may require a different
drug. Do not give your medicine to other people or use it for other
infections, unless your doctor specifically directs you to.
* Before having surgery or any other medical or dental treatment, be sure
to tell your doctor or dentist that you are taking erythromycin.
* Not all erythromycin products are chemically equivalent. However, they
all produce the same therapeutic effect. Discuss with your doctor or
pharmacist which forms of erythromycin are appropriate for you, and then
choose the least expensive product among those recommended.
* Some of these products contain the color additive FD&C Yellow No. 5
(tartrazine), which can cause allergic-type reactions (difficulty in
breathing, rash, fainting) in certain susceptible individuals.
* Be sure to tell your doctor if you are pregnant. Although erythromycin
appears to be safe during pregnancy, extensive studies in humans have not been
conducted. Also, tell your doctor if you are breast-feeding an infant. Small
amounts of this medication pass into breast milk and may temporarily alter the
bacterial balance in the intestinal tract of the nursing infant, resulting in
diarrhea.
----------------
The material contained here is "FOR INFORMATION ONLY" and should not replace
the counsel and advice of your personal physician. Promptly consulting your
doctor is the best path to a quick and successful resolution of any medical
problem.