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- $Unique_ID{BRK01461}
- $Pretitle{}
- $Title{What is "Pheochromocytoma"?}
- $Subject{pheochromocytoma blood pressure surgery cancer cancers neoplasm
- neoplasms tumor chromaffin catecholamines episodic sweating headaches
- palpitations flushing abdominal pain constipation shortness breath nausea
- vomiting adrenal gland glands computed tomography ct magnetic resonance
- imaging mri scintigraphy radio isotopes tumors neoplasms pheochromocytomas
- pheochromocytomata chromaffins catecholamine sweat headache palpitation flush}
- $Volume{B-22}
- $Log{}
-
- Copyright (c) 1991-92,1993 Tribune Media Services, Inc.
-
-
- What is "Pheochromocytoma"?
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-
- QUESTION: At age 47, my husband has been diagnosed with a rare type of high
- blood pressure, for which surgery is being advised. Although his doctor tried
- to explain the facts about a "pheochromocytoma," we are still confused and
- distressed. We hope you will find this question interesting enough to publish
- an answer in your column.
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-
- ANSWER: It is certainly an interesting condition, but can also be most
- confusing. Even the name is more than most people can manage to say. Broken
- down to its Greek origins the word means "dusky (pheo) colored (chromo) cell
- (cyt) tumor (oma)", and it is in fact a tumor of chromaffin cells that secrete
- chemicals called catecholamines. These chemicals produce a number of
- reactions in the body. Typically a patient will experience episodic sweating,
- headaches, and palpitations and will be found to have an elevated blood
- pressure when tested. Additional symptoms of flushing, abdominal pain,
- constipation, shortness of breath, nausea and vomiting may occur, but not all
- symptoms occur in all patients. At first the symptoms come on infrequently
- and last for but fifteen minutes or so, but with passing time, both the
- severity and frequency of the attacks increase. Although the physical
- examination may be normal, a urine test will show an increased level of
- catecholamines. Testing a 24 hour urine specimen for various other chemicals
- which result from the chemical breakdown of catecholamines will usually lead
- to an accurate diagnosis. The next problem is to determine the location of
- the tumors. They average 5 to 6 cm. in size, usually weigh from 50 to 200 gm,
- but can grow as large as several kilograms. About 80 percent of the time they
- are found in the adrenal gland, which perches on the kidney. However they may
- be found in the glands on both sides of the body (in about 10 percent of the
- cases) and may be located in other areas of the body as well. A variety of
- imaging techniques such as computed tomography (CT) and magnetic resonance
- imaging (MRI) are used to complement scintigraphy, which uses radio active
- isotopes to locate the tumors. Surgery is needed to permanently remove the
- tumors, and the patient usually passes through a period of medical management
- when various medications are used to assure that the hypertension and other
- symptoms are controlled before the operation is performed.
-
- ----------------
-
- The material contained here is "FOR INFORMATION ONLY" and should not replace
- the counsel and advice of your personal physician. Promptly consulting your
- doctor is the best path to a quick and successful resolution of any medical
- problem.
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