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- $Unique_ID{BRK00736}
- $Pretitle{}
- $Title{Are There Any Tests to Predict Drug Allergy?}
- $Subject{medication medications medicine medicines drug allergy reactions
- allergic reactions rash hives swelling drugs allergies fever wheezing immune}
- $Volume{R-0}
- $Log{
- The Process of an Allergic Reaction*0001201.scf
- Histamine Release Causes Allergy Symptoms*0001202.scf
- The Function of IgG in an Allergic Reaction*0001203.scf}
-
- Copyright (c) 1991-92,1993 Tribune Media Services, Inc.
-
-
- Are There Any Tests to Predict Drug Allergy?
-
-
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-
- QUESTION: Having just recovered from the problems of a drug allergy brought
- on by a prescription medication. I was wondering if there wasn't some way to
- have predicted that this might have happened. Aren't there any tests
- available, and how does the doctor know that it was an allergy that produced
- all my symptoms?
-
- ------------------------------------------------------------------------------
-
- ANSWER: As a general rule, it is impossible to predict which patient may have
- an allergic reaction to a drug, or to any other substance for that matter. An
- allergy is an exaggerated sensitivity to a substance that usually produces no
- reactions in most other people. A careful case history of previous
- experiences with medications, or the presence of allergic reactions to
- pollens, food, or animals may alert a physician to the possibility that the
- patient is a sensitive individual, but does not guarantee that there will be a
- reaction to the needed medication. Of course, any adverse experiences with a
- medication previously would be sufficient warning not to use that particular
- medication again. However, even when a medication has been used successfully
- in the past, without any trouble, there is still no assurance that it won't
- provoke a reaction on this new occasion. When the disease is life
- threatening, and only one medication can do the job, a skin test may be used
- to evaluate the sensitivity of the patient, and help in deciding whether or
- not to use the medication. Many so called allergic reactions are in reality a
- side effect, and do not involve the body's immune system; and testing of the
- immune response to the substance reveals this. Abdominal upsets (including
- diarrhea), sleepiness, and jittery feelings are samples of some reactions that
- are not normally provoked by allergic mechanisms. When a true allergic
- symptoms is discovered, such as a rash, hives, swelling, drug fever, or
- wheezing, the first step is to discontinue the use of the medication
- immediately. A careful history is sought to try to link the taking of the
- medication to the onset of the symptoms. It is important to report the use of
- any other medications taken at the same time, including over-the-counter
- preparations, vitamins, pain killers and the like, as they may have been part
- of the reaction. Once the drug has been stopped, the disappearance of the
- symptoms within 24 to 48 hours makes it highly likely that the new medication
- was the cause of the reaction, and this fact should not only be noted on the
- chart, but remembered by the patient, and reported to any physician who is
- faced with prescribing treatment.
-
- ----------------
-
- The material contained here is "FOR INFORMATION ONLY" and should not replace
- the counsel and advice of your personal physician. Promptly consulting your
- doctor is the best path to a quick and successful resolution of any medical
- problem.
-