home
***
CD-ROM
|
disk
|
FTP
|
other
***
search
/
DP Tool Club 17
/
CD_ASCQ_17_101194.iso
/
vrac
/
med9408d.zip
/
M9480794.TXT
< prev
next >
Wrap
Text File
|
1994-08-27
|
2KB
|
32 lines
Document 0794
DOCN M9480794
TI Evaluation of the sensitivity, specificity, and predictive value of
monoclonal antibody 3F6 for the detection of Pneumocystis carinii
pneumonia in bronchoalveolar lavage specimens and induced sputum.
DT 9410
AU Wazir JF; Macrorie SG; Coleman DV; Department of Cytopathology, Saint
Mary's Hospital, London, UK.
SO Cytopathology. 1994 Apr;5(2):82-9. Unique Identifier : AIDSLINE
MED/94312679
AB The sensitivity and specificity of different staining procedures for the
detection of Pneumocystis carinii organisms were compared. Three
conventional stains (Papanicolaou, Giemsa and Grocott's) and one
immunocytochemical stain using 3F6 antibody were used on smears prepared
from the same specimen. Bronchoalveolar lavage (BAL) and induced sputum
(IS) specimens were used for this purpose. One hundred and sixty-five
episodes from 142 patients were investigated by the four different
staining techniques. Cysts of P. carinii were detected in 64 episodes
from 63 patients. Immunocytochemical staining with 3F6 was found to be
slightly more sensitive at detecting the cysts than Grocott's, Giemsa,
or Papanicolaou stain.
DE Antibodies, Monoclonal/*DIAGNOSTIC USE AIDS-Related Opportunistic
Infections/DIAGNOSIS Bronchoalveolar Lavage Fluid/*MICROBIOLOGY
Evaluation Studies Human Immunohistochemistry Pneumocystis
carinii/ISOLATION & PURIF Pneumonia, Pneumocystis carinii/*DIAGNOSIS
Predictive Value of Tests Sensitivity and Specificity
Sputum/*MICROBIOLOGY Stains and Staining JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).