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1994-08-27
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Document 0675
DOCN M9480675
TI The current trend in genital herpes. Progress in prevention.
DT 9410
AU Corey L; Department of Laboratory Medicine, University of Washington,;
Seattle 98144.
SO Sex Transm Dis. 1994 Mar-Apr;21(2 Suppl):S38-44. Unique Identifier :
AIDSLINE MED/94317079
AB Recent serosurveys indicate that the prevalence of genital herpes has
continued to increase even during the decade of HIV. Much of this
continued transmission is due to the difficulty of identifying the
subclinical carrier of HSV-2. The development of serologic assays that
accurately distinguish HSV-1 from HSV-2 infection now allow such persons
to be identified, and recent studies indicate almost all HSV-2
seropositives have symptoms and signs of reactivation HSV-2. Moreover,
over 50% will shed virus subclinically in the genital tract. This
underestimation of this reactivation rate appears to be another factor
in the continued spread of the virus throughout the population. The
development of an HSV vaccine is imperative if we are to control this
rapidly increasing infection.
DE Adolescence Adult Carrier State/DIAGNOSIS/EPIDEMIOLOGY/*PREVENTION &
CONTROL Female Herpes Genitalis/DIAGNOSIS/EPIDEMIOLOGY/*PREVENTION &
CONTROL Herpesvirus 1, Human Herpesvirus 2, Human Human Male
Recurrence Seroepidemiologic Methods Support, U.S. Gov't, P.H.S.
JOURNAL ARTICLE REVIEW REVIEW, TUTORIAL
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).