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1994-10-01
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Document 0157
DOCN M94A0157
TI Recent developments in psoriatic arthritis.
DT 9412
AU Cuellar ML; Silveira LH; Espinoza LR; Section of Rheumatology, LSU
Medical Center, New Orleans; 70112-2822.
SO Curr Opin Rheumatol. 1994 Jul;6(4):378-84. Unique Identifier : AIDSLINE
MED/94347567
AB Psoriatic arthritis affects 5% to 7% of patients with psoriasis.
Genetic, immunologic, and environmental factors play a role in its
pathogenesis. The role of inflammatory cytokines has been better
defined, and recent immunohistochemical studies of the synovial
membranes have shown important differences and similarities between
psoriatic arthritis and rheumatoid arthritis. The association of
psoriatic arthritis with infection, particularly HIV, remains an
interesting observation. The most common clinical presentation appears
to be peripheral polyarticular, and extra-articular manifestations
including the SAPHO (synovitis, acne, pustulosis, hypertosis, and
osteitis) syndrome are not common. Methotrexate and sulfasalazine
therapy are effective in patients who do not respond to nonsteroidal
anti-inflammatory drugs.
DE *Arthritis, Psoriatic/DIAGNOSIS/EPIDEMIOLOGY/ETIOLOGY/THERAPY Human
JOURNAL ARTICLE REVIEW REVIEW, TUTORIAL
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).