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M94A0029.TXT
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1994-10-01
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Document 0029
DOCN M94A0029
TI Prophylactic vaccines, risk behavior change, and the probability of
eradicating HIV in San Francisco.
DT 9412
AU Blower SM; McLean AR; Epidemiology Department, School of Public Health,
University of; California at Berkeley 94720.
SO Science. 1994 Sep 2;265(5177):1451-4. Unique Identifier : AIDSLINE
MED/94353245
AB Theory is linked with data to assess the probability of eradicating
human immunodeficiency virus (HIV) in San Francisco through the use of
prophylactic vaccines. The necessary vaccine efficacy levels and
population coverage levels for eradication are quantified. The likely
impact of risk behavior changes on vaccination campaigns is assessed.
The results show it is unlikely that vaccines will be able to eradicate
HIV in San Francisco unless they are combined with considerable
reductions in risk behaviors. Furthermore, if risk behavior increases as
the result of a vaccination campaign, then vaccination could result in a
perverse outcome by increasing the severity of the epidemic.
DE Adult *AIDS Vaccines Disease Outbreaks/PREVENTION & CONTROL
*Homosexuality Human HIV Infections/EPIDEMIOLOGY/*PREVENTION & CONTROL
Immunization Programs Male Probability *Risk-Taking San
Francisco/EPIDEMIOLOGY Support, Non-U.S. Gov't Support, U.S. Gov't,
P.H.S. JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).