home
***
CD-ROM
|
disk
|
FTP
|
other
***
search
/
The Pier Shareware 6
/
The_Pier_Shareware_Number_6_(The_Pier_Exchange)_(1995).iso
/
026
/
med9408e.zip
/
M9480856.TXT
< prev
next >
Wrap
Text File
|
1994-09-05
|
2KB
|
33 lines
Document 0856
DOCN M9480856
TI Antibody profile and isotypic patterns on HIV infected patients under
drug treatment.
DT 9410
AU Rivera L; Montealegre F; Diaz AM; Univ. of P.R.
SO Abstr Gen Meet Am Soc Microbiol. 1994;94:484 (abstract no. T-11). Unique
Identifier : AIDSLINE ASM94/94313089
AB In this study we correlated the isotype and specificity of the IgG
antibody response from 100 Puerto Rican HIV-infected patients with the
treatment which they were given. Western Blots have been performed to
determine the isotype as well as protein specificity of antibodies
contained in the patient's serum. Clinical data like sex, age, rate of
infection, stage according to the classification of CDC, number of T-CD4
cells, antiviral treatment and treatment against opportunistic infection
were collected from patient's records that were treated in P.R. Concra.
The detection of isotypes by Western Blots allowed an evaluation of the
host response to specific viral proteins and the effect of drug therapy
in the humoral response. The results of this work would be a useful tool
for finding of the best treatment against the infection by HIV-1. The
treatment which increases the reactivity of isotypes like IgG1, and IgG3
which have an important role in defense as neutralizing antibodies and
anti-HIV ADCC, have been determined.
DE Acquired Immunodeficiency Syndrome/BLOOD/*DRUG THERAPY/ *IMMUNOLOGY
Antibody Formation Antiviral Agents/*THERAPEUTIC USE Blotting, Western
Female Human HIV Infections/BLOOD/*DRUG THERAPY/*IMMUNOLOGY *HIV-1
IgG/*BLOOD/CLASSIFICATION Immunoglobulin Isotypes/*BLOOD Male T4
Lymphocytes/IMMUNOLOGY MEETING ABSTRACT
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).