home
***
CD-ROM
|
disk
|
FTP
|
other
***
search
/
HaCKeRz KrOnIcKLeZ 3
/
HaCKeRz_KrOnIcKLeZ.iso
/
drugs
/
prozac.interactions
< prev
next >
Wrap
Text File
|
1996-05-06
|
3KB
|
55 lines
Newsgroups: alt.drugs
From: lamont@hyperreal.com (Lamont Granquist)
Subject: Medline info on drug-drug interactions
Message-ID: <1993Oct25.205133.10949@beaver.cs.washington.edu>
Date: Mon, 25 Oct 93 20:51:33 GMT
----------------------------------------------------------------------
On drug-drug interactions:
Accession Number: 93000357. Citation: 2 of 4
Author: Strassman-R-J.
Title: Human hallucinogen interactions with drugs affecting
serotonergic neurotransmission.
Source: Neuropsychopharmacology. 1992 Nov. 7(3). P 241-3.
Abstract: The absence of relevant human research studies of
hallucinogenic drugs has not curtailed their unsupervised
use. Two cases are presented that suggest decreased
sensitivity to the serotonergic hallucinogens psilocybin and
LSD induced by drugs with effects on serotonergic
neurotransmission, allopurinol and fluoxetine. These reports
suggest that hallucinogens' effects in humans are mediated by
serotonergic receptors.
Accession Number: 92272338. Citation: 3 of 4
Author: Picker-W. Lerman-A. Hajal-F.
Title: Potential interaction of LSD and fluoxetine [letter]
Source: Am-J-Psychiatry. 1992 Jun. 149(6). P 843-4.
Accession Number: 93359556. Citation: 1 of 45
Author: McCann-U-D. Ricaurte-G-A.
Title: Reinforcing subjective effects of (+/-)
3,4-methylenedioxymethamphetamine ("ecstasy") may be
separable from its neurotoxic actions: clinical evidence.
Source: J-Clin-Psychopharmacol. 1993 Jun. 13(3). P 214-7.
Abstract: (+/-)3,4-Methylenedioxymethamphetamine (MDMA), a synthetic
amphetamine derivative used recreationally by humans, damages
brain serotonin neurons in experimental animals. In
preclinical studies, serotonin reuptake inhibitors block
MDMA-induced serotonin release; they also block MDMA
neurotoxicity. Whether serotonin reuptake inhibitors also
block MDMA's psychoactive effects in humans has not been
established. Reported herein are four individuals who
describe their experiences after ingesting fluoxetine, a
potent and selective serotonin reuptake inhibitor, before
MDMA ingestion. Their reports indicate that fluoxetine does
not block MDMA's reinforcing subjective effects and raise the
possibility that MDMA's psychoactive effects may be separable
from its neurotoxic actions.