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The Datafile PD-CD 5
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DATAFILE_PDCD5.iso
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rasmol
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antibody
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!Antibody
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CDRLY-A_SC
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1996-03-03
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1KB
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76 lines
zap
set hourglass on
load "fab_lyso.pdb"
rotate z -89
rotate y 25
rotate x -10
wireframe off
#SPACEFILL CPK
spacefill
script clrleg.scr
echo Hen egg white lysozyme (left) bound to Fab (right).
echo . (Hydrogens [white] are not shown because they cannot be
echo . resolved by X-ray diffraction.)
pause
#COLOR BY CHAIN
select :l
color green
select :h
color orange
select :y
color magenta
#LABEL CHAINS
set fontsize 15
select atomno=1780
label HEAVY CHAIN
select atomno=1568
label .LIGHT CHAIN
select atomno=3682
label LYSOZYME
select atomno=3306
label HINGE
script clrleg.scr
script wave1.scr
pause
#BACKBONE
select all
spacefill off
backbone 0.3
echo
echo Backbone representation.
pause
#LABELS OFF
select all
label off
pause
#Fv + LYSOZYME ONLY
restrict 1-117:h or 1-108:l or :y
echo
echo Fv is the smallest antibody fragment which can bind antigen.
pause
#Fv ONLY
reset
rotate z -89
rotate y 25
rotate x -10
select atomno=307 #this atom is not part of the backbone so is invisible
color white
set fontsize 25
#color label white - this makes subsequent labels lose their atomcolor
label Fv
script fv.scr
backbone 0.15
echo Fv: "Fragment" containing the "Variable" domains of the H+L chains.
pause
#LARGER
zoom 200
pause