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- **********************************************
- * Flagella basal body rod proteins signature *
- **********************************************
-
- Many bacterial species swim actively by means of flagella [1]. The flagella
- organelle is made of three parts: the basal body, the hook and the filament.
- The basal body consists of four rings (L,P,S, and M) mounted on a central rod.
- In Salmonella typhimurium and related organisms the rod has been shown [2] to
- consist of four different, yet evolutionary related proteins: in the distal
- portion of the rod there are about 26 subunits of protein flgG and in the
- proximal portion there are about 6 subunits each of proteins flgB, flgC, and
- flgF.
-
- These four proteins contain in their N-terminal section a highly conserved
- asparagine-rich domain that we have used as a signature pattern.
-
- This pattern is also found in the flagella hook protein flgE and in the
- Central Section Of The Flaa Flagella Core Protein Of The Spirochaetaceae
- Borrelia burgdorferi.
-
- -Consensus pattern: [GAR]-x(9)-[LIVM]-x-[GAST]-[SNA]-N-[LIVM]-A-N-x(2)-[ST]
- -Sequences known to belong to this class detected by the pattern: ALL.
- -Other sequence(s) detected in SWISS-PROT: NONE.
- -Last update: June 1994 / Pattern and text revised.
-
- [ 1] Macnab R.M.
- (In) Escherichia coli and Salmonella typhimurium: cellular and molecular
- biology, Neidhardt F.C., Ingraham J.L., Low K.B., Magasanik B.,
- Schaechter M., Umbarger H.E., Eds., pp70-83, American society for
- Microbiology, Washington D.C, (1987).
- [ 2] Homma M., Kutsukake K., Hasebe M., Iino T., Macnab R.M.
- J. Mol. Biol. 211:465-477(1990).
-