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- **********************************
- * Ribosomal protein L3 signature *
- **********************************
-
- Ribosomal protein L3 is one of the proteins from the large ribosomal subunit.
- In Escherichia coli, L3 is known to bind to the 23S rRNA and may participate
- in the formation of the peptidyltransferase center of the ribosome. It belongs
- to a family of ribosomal proteins which, on the basis of sequence
- similarities [1,2,3,4], groups:
-
- - Eubacterial L3.
- - Archaebacterial Halobacterium marismortui HmaL3 (HL1).
- - Cyanelle L3.
- - Yeast L3 (also known as trichodermin resistance protein) (gene TCM1).
- - Arabidopsis thaliana L3 (genes ARP1 and ARP2).
- - Mammalian L3 (L4).
- - Mammalian mitochondrial L3.
- - Yeast mitochondrial YmL9 (gene MRPL9).
-
- As a signature pattern, we selected a conserved region located in the central
- section of these proteins.
-
- -Consensus pattern: F-x(6)-[DN]-x(2)-[AGS]-x-[ST]-x-G-[KRH]-G-x(2)-G-x(3)-R
- -Sequences known to belong to this class detected by the pattern: ALL.
- -Other sequence(s) detected in SWISS-PROT: NONE.
- -Last update: June 1994 / Text revised.
-
- [ 1] Arndt E., Kroemer W., Hatakeyama T.
- J. Biol. Chem. 265:3034-3039(1990).
- [ 2] Graack H.-R., Grohmann L., Kitakawa M., Schaefer K.L., Kruft V.
- Eur. J. Biochem. 206:373-380(1992).
- [ 3] Herwig S., Kruft V., Wittmann-Liebold B.
- Eur. J. Biochem. 207:877-885(1992).
- [ 4] Otaka E., Hashimoto T., Mizuta K., Suzuki K.
- Protein Seq. Data Anal. 5:301-313(1993).
-