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- *****************************************************
- * Cell cycle proteins ftsW / rodA / spoVE signature *
- *****************************************************
-
- A number of prokaryotic proteins involved in cell cycle processes have been
- found [1,2] to be structurally related, these proteins are:
-
- - Escherichia coli cell division protein ftsW. The exact function of ftsW is
- not known.
- - Escherichia coli rod shape-determining protein rodA. It is required for the
- expression of the enzymatic activity of PBP2, which is thought to
- participate in the synthesis of peptidoglycan during the initiation of cell
- elongation.
- - Bacillus subtilis stage V sporulation protein E (spoVE). The exact function
- of spoVE in endospore formation is not known.
-
- All these proteins are hydrophobic and contain about 400 residues. We have
- selected the best conserved region, a hexapeptide, as a signature pattern for
- these proteins.
-
- -Consensus pattern: T-D-F-I-F-A
- -Sequences known to belong to this class detected by the pattern: ALL.
- -Other sequence(s) detected in SWISS-PROT: NONE.
- -Last update: November 1990 / First entry.
-
- [ 1] Ikeda M., Sato T., Wachi M., Jung H.K., Ishino F., Kobayashi Y.,
- Matsuhashi M.
- J. Bacteriol. 171:6375-6378(1989).
- [ 2] Joris B., Dive G., Henriques A., Piggot P.J., Ghuysen J.M.
- Mol. Microbiol. 4:513-517(1990).
-