home *** CD-ROM | disk | FTP | other *** search
- Newsgroups: sci.math.stat
- Path: sparky!uunet!decwrl!csus.edu!beach.csulb.edu!rcrump
- From: rcrump@beach.csulb.edu (Randy Crump)
- Subject: Differences in diagnostic utility: Tests?
- Message-ID: <RCRUMP.92Sep3163243@beach.csulb.edu>
- Lines: 20
- Sender: rcrump@beach.csulb.edu (Randy Crump)
- Organization: Cal State Long Beach
- Date: Thu, 3 Sep 1992 23:32:46 GMT
-
- I work in a clinical research setting where we frequently examine
- parameters obtained during exercise stress testing in an effort
- to develop methods that will permit an increased sensitivity and
- specificity for the prediction of coronary artery disease. Our
- usual approach is to apply two different variables or sets of
- variables to the same sample, and then ask which provides the
- better diagnostic utility.
-
- I have been structuring an agreement matrix with the cells
- containing those patients correctly and incorrectly classified by
- each variable set; I then test for a difference in the discordance
- using McNemar's test. I am also looking at comparing the areas
- under the two ROC curves.
-
- I would appreciate any suggestions of any other methods I should
- be considering.
-
- Thank you,
-
- Randy Crump
-