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- From: weemba@sagi.wistar.upenn.edu (Matthew P Wiener)
- Newsgroups: sci.med.aids
- Subject: Re: HIV/AIDS Link -- followup inquiry
- Message-ID: <1993Jan26.170451.6870@cs.ucla.edu>
- Date: 26 Jan 93 14:54:32 GMT
- References: <1993Jan26.043240.6847@cs.ucla.edu>
- Sender: news@noc2.dccs.upenn.edu
- Reply-To: weemba@sagi.wistar.upenn.edu (Matthew P Wiener)
- Organization: The Wistar Institute of Anatomy and Biology
- Lines: 44
- Approved: david@stat.com (David Dodell)
- Note: Copyright 1992, Dan R. Greening. Non-commercial reproduction allowed.
- Nntp-Posting-Host: sole.cs.ucla.edu
- Archive-Number: 39
-
- In article <1993Jan26.043240.6847@cs.ucla.edu>, quilty@PHILOS (Lulu of the lotus-eaters) writes:
- >In a responding post, Matthew P Wiener, has largely denounced
- >Duesberg's scepticism; and by extention, I believe, my question.
-
- I've not denounced his skepticism. It's the extreme weakness of his
- arguments, which rely on too much bad reasoning and incorrect data,
- that I've largely denounced.
-
- >However, this is not the case for HIV. Even if it infects 90% of T4
- >cells, it remains latent in all but .01% of these cells at any given
- >time. This latency is not *even*, but *especially* during the late
- >stages of AIDS.
-
- This is significant if you assume that HIV killing T-cells is the cause
- of AIDS. But there's no particular reason to believe this--it was just
- the first and most obvious conclusion to jump to when HIV was discovered
- --and so the objection is not worth much.
-
- Autoimmunity theories seem more likely. HIV's surface protein, gp120,
- has some homology with MHC(II)--enough so that both bind to CD4. Which
- means that antibodies against gp120 might crossreact with MHC(II), and
- the immune system self-destructs.
-
- >[argument omitted] The long and short of it is the the HIV/AIDS
- >explanation has a *BIG* conceptual gap in the middle of it.
-
- No, the long and short of it is that Duesberg's objection has the *BIG*
- conceptual gap--why should anyone assume the disease is caused by HIV
- killing T-cells? It almost certainly isn't, as the long and detailed
- numbers you cite indicate.
-
- > I won't dogmatically
- >conclude that this gap can't be filled; but neither will I
- >dogmatically believe the hypothesis based simply on the word of a
- >medical-research establishment deeply intermeshed with political
- >biases, and a standard of truth subsumed to personal power games
- >(by Gallo, particularly -- but others also).
-
- So don't dogmatically believe the words of the medical-research
- establishment. Seek out nurses whose only known risk for AIDS was
- a needlestick from HIV+ blood, and ask them what _they_ think of the
- poppers/lifestyle theory.
- --
- -Matthew P Wiener (weemba@sagi.wistar.upenn.edu)
-