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- Xref: sparky rec.food.veg:12392 misc.health.alternative:654 sci.med.nutrition:1990
- Path: sparky!uunet!nwnexus!sftwks!bradbury
- From: bradbury@sftwks.UUCP (Robert Bradbury)
- Newsgroups: rec.food.veg,misc.health.alternative,sci.med.nutrition
- Subject: Re: "The miracle of fasting" by Paul C. Bragg
- Summary: Energy generation during fasting/calorie restriction
- Message-ID: <230@sftwks.UUCP>
- Date: 17 Jan 93 01:40:10 GMT
- References: <1993Jan13.005830.28513@imagen.com> <1993Jan14.235554.15921@imagen.com> <1993Jan15.165018.15492@walter.bellcore.com>
- Followup-To: rec.food.veg
- Organization: Softworks Ltd, Seattle, WA
- Lines: 85
-
- In article <1993Jan15.165018.15492@walter.bellcore.com>
- kenl@origami.cc.bellcore.com (Ken Lehner) writes:
- >In article <1993Jan14.235554.15921@imagen.com>, avi@eagle.imagen.com writes:
- >
- >|> For example, he walked 30 miles non-stop in Death Valley, CA in August
- >|> (one of the Hottest places in the world) WHILE fasting and he was in
- >|> his 50's and the 10 young College Athlethes who were NOT fasting who
- >|> joined him, all collapsed before him and none of them finished the 30 mile
- >|> track, but him. If I remember correctly, (and I could be wrong on this
- >|> detail) he was on his 7th day of a 10-day fast !
- >
- >I'm most skeptical about this anecdote. Living for 7 days requires
- >energy: where does he get it from? Glycogen in the muscles must be
- >replenished. He either eats or he consumes body fat (and/or muscle). If
- >he has such a healthy diet, he can't have very much body fat to spare
- >(like 4 pounds in a 7 day fast).
-
- The energy comes from the proteins in the body. After all glucose,
- glycogen and fat are exhausted the body relies on gluconeogenesis
- (generation of glucose from amino acids) for energy. Now, if this
- were to continue for an extended period of time the person would
- waste away (as is seen during starvation) but for the short periods
- associated with fasts our bodies can handle it. Do you really think
- the primitive man would go through life getting 3 square meals a day,
- every day? All animal species will encounter periods when there are
- food shortages and must have adaptive mechanisms to handle it.
- Now, the interesting question is "why" do fasting or calorie
- restriction reduce the aging rate? Since you body needs amino
- acids for gluconeogenesis it directs cells to break down proteins
- and release amino acids. Cells have natural pathways which break
- down old/damaged proteins which seem to be accelerated under conditions
- of calorie restriction. Proteins have an "average" half-life of 24 hours,
- some last only minutes, others several days. In the calorie restricted
- state the half-life is probably shifted so proteins are degraded before
- they have sustained as much damage as in a "well-fed" individual.
- Less damaged proteins allows your body to function more efficiently.
- So, I'm not suprised that a fasting individual could outperform a
- well-fed individual.
- >
- >In the world of triathlons, there is a condition known as "bonking". It
- >is a state of light-headedness, inability to exert much force, and a
- >serious desire to eat. It occurs after the body has depleted it's
- >available energy resources, and can result after an hour or two of aerobic
- >exercise. I wasn't aware of anything that could prevent this except for
- >correct fueling before and during the activity.
- >
- The "bonking" results because the body has run out of available fuel.
- It takes at least several hours to turn on the genes involved in
- protein breakdown and gluconeogenesis and get them functioning at
- a level which can support physical activity. They also probably
- were not designed to support the activity required in marathon
- running (note the fasting individual was *walking*). Our bodies
- aren't designed for long term aerobic activity, there are obviously
- other animals (e.g. migratory birds) who can expend a great deal
- of energy over a long time and have no problems with it.
-
- >Walking 30 miles in an extremely hot, arid environment has little to do
- >with fasting, and everything to do with correct hydration and one's ability
- >to maintain body temperature. Just why did these College Athletes (and
- >why the caps?) collapse? To what aspect of fasting does he attribute this
- >"ability", and just what is it that happens to his physiology? Name some
- >"incredible athletic feats" of his (walking 30 miles isn't one of them, at
- >least to me). Incredible is biking across the US in under 10 days;
- >incredible (and not really bright :^) is scaling Everest without
- >carrying oxygen; incredible is the 65 year old woman who ran something
- >like 390 miles in 6 days (and you BET she was eating).
-
- The body responds to conditions of "heat" or "stress" by manufacturing
- "heat-shock" proteins. These are proteins found in all animals and
- play a key role in maintaining proteins in their proper folded form
- (heat tends to cause proteins to unfold and function improperly).
- I would suspect that a fasting individual probably has higher levels
- of heat shock proteins (low food intake is considered "stress") than
- well-fed individuals and that would easily explain his better ability
- to tolerate the heat.
-
- "Incredible" is something which depends on your perspective.
- I seem to remember a fairy-tale about a hare and a tortise....
- While individuals who fast periodically may not be able to run
- marathons he just might outlive those people who choose to do that.
- --
- Robert Bradbury uunet!sftwks!bradbury
-
- Death is an imposition on the human race, and no longer acceptable
- Alan Harrington, The Immortalist (1969)
-