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- Date: Tue, 26 Jan 1993 13:41:28 -0800
- Reply-To: Harry Mangalam <mangalam@SALK-SC2.SDSC.EDU>
- Sender: "INFO-GCG: GCG Genetics Software Discussion"
- <INFO-GCG@UTORONTO.BITNET>
- From: Harry Mangalam <mangalam@SALK-SC2.SDSC.EDU>
- Subject: Re: Prokaryotic TFD?
- Comments: To: GAGUTMAN@UCI.EDU, INFO-GCG@UTORONTO.BITNET
- Lines: 25
-
- >Is there a prokaryotic equivalent of the Transcription Factor Database,
- >to identify potential protein-binding motifs in E. coli DNA
- >in particular?
-
-
- Hi George,
-
- Just happened to checking the list and saw your post. In fact, the TFD
- includes prokaryotic motifs, as well as the euk ones. The latest version
- can be got at ncbi.nlm.nih.gov in /pub/repository/tfd (or ..TFD ?). It may
- not be as detailed as you want, but it's free and it's easily available.
- You might also want to check out Doug Prestridge's program Signalscan to
- use as a way of searching your DNA for the motifs. I'm not sure the GCG
- programs can perform a similar function (corrections, please?), but you
- could probably build a little script that could take a sequence, do a
- "findpatterns" with it, then go to the next.
-
- Cheers
- Harry
-
- Harry Mangalam Vox:(619) 453-4100, x250
- Dept of Biocomputing Fax:(619) 552-1546
- The Salk Institute 1' mangalam@salk-sc2.sdsc.edu
- 10010 N Torrey Pines Rd 2' hjm@salk-sgi.sdsc.edu
- La Jolla CA 92037 3' mangalam@salk.bitnet
-