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- From: tsornas@dec5.ulb.ac.be (Thierry Sornasse)
- Newsgroups: bionet.immunology
- Subject: Re: Advice for Immunology Paper
- Message-ID: <1104@rc1.vub.ac.be>
- Date: 25 Jan 93 14:39:09 GMT
- References: <1993Jan25.062940.7576@netnews.louisville.edu>
- Sender: news@rc1.vub.ac.be
- Distribution: world
- Organization: Free University Brussels - Belgium - Department of Molecular Biology
- Lines: 37
-
- Hi networker,
-
- I am a graduate student in immunology (probably PhD. in 6 months) and I would
- be pleased to help you. I thing there are some "hot spot" in immunology today, I
- hope you'll find something that fit your need among these proposals.
-
- Antigen presenting cells: the immune response is often seen only at the output
- level, I mean at the effector level. In fact, the triggering of the immune
- response depends on the very subtil relationship between antigen presenting cells
- and the T helper cells. I think there are two points that worth a closer look.
- 1) The role of the lymphoide dendritic cells (or dendritic leukocytes) in the
- initiation of the immune response.
- 2) The regulation of the immune response and the immune tolerance by the
- modulation of the costimulatory signal (the second signal require by the T helper
- cells to be fully activated).
-
- Gene knock down mice: the relatively new technique of the gene knock down has
- allowed the production of different strains of mice deficient for a wide range of
- function: interleukines or Invarient chain (linked to MHC II) or different
- subunit of the immunoglobulin molecule....
- This new type of material will allow the immunologist to discover the precise
- role of a large set of immunological elements.
-
- I think there are too many exciting subject in immunology to list it all.
- If you do not find what you are looking for, I think that you will find a wide
- range of up-to-date topics in "Immunology Today".
-
- Good Work
-
- Don't hesitate to ask me more details
-
- (Forgive me for my exotic english)
-
- Thierry Sornasse
- Univesite Libre de Bruxelles
- Lab. de Physiologie Animale
- Elm: tsornas@dec5.ulb.ac.be
-