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- Path: sparky!uunet!europa.eng.gtefsd.com!paladin.american.edu!howland.reston.ans.net!usc!cs.utexas.edu!torn!nott!cunews!droberts
- From: droberts@alfred.carleton.ca (David Roberts)
- Subject: MDA and MDMA neurotoxicity
- Message-ID: <droberts.728244468@cunews>
- Summary: References for MDA and MDMA neurotoxicity
- Keywords: MDA, MDMA, NEUROTOXICITY, DRUGS
- Sender: news@cunews.carleton.ca (News Administrator)
- Organization: Carleton University
- Date: Thu, 28 Jan 1993 18:07:48 GMT
- Lines: 96
-
- Those who are think that MDA and MDMA are not neurotoxic may find the
- following references helpful:
-
- Axt KJ, Mullen CA, Molliver ME (1992) Cytopathologic features indicative
- of 5-hydroxytryptamine axon degeneration are observed in rat brain after
- administration of d- and l-methylenedioxyamphetamine. Ann. NY Acad.
- Sci. 648: 244-247
-
- Battaglia G, Yeh SY, O'Hearn E, Molliver ME, Kuhar MJ, DeSouza EB (1987)
- 3,4-Methylenedioxymethamphetamine and 3,4-methyleneamphetamine destroy
- terminals in rat brain: quantification of neurodegeneration by measurement
- of [3H]-paroxetine labelled seroto nin uptake sites. J. Pharm. exp.
- Ther. 242: 911-916
-
- Battaglia G, Sharkey J, Kuhar MJ, De Souza EB (1991) Neuroanatomic
- specificity and time course of alterations in rat brain serotonergic
- pathways induced by MDMA (3,4-methylenedioxymethamphetamine): Assessment
- using quantitative autoradiography. Synapse 8 : 249-260
-
- Johnson M, Stone DM, Bush LG, Hanson GR, Gibb JW (1989) Glucocorticoids
- and 3,4-methylenedioxyamphetamine (MDMA)-induced neurotoxicity. Eur. J.
- Pharmacol. 161: 181-188
-
- Johnson MP, Huang X, Nichols DE (1991) Serotonin neurotoxicity in rats
- after combined treatment with a dopaminergic agent followed by a
- nonneurotoxic 3, 4-methylenedioxymethamphetamine (MDMA) analogue.
- Pharmacol. Biochem. Behav. 40: 915-922
-
- Johnson MP, Nichols DE (1991) Combined administration of a non-neurotoxic
- 3,4-methylenedioxymethamphetamine analogue with amphetamine produces
- serotonin neurotoxicity in rats. Neuropharmacology 30: 819-822
-
- Markert LE, Roberts DCS (1991) 3,4-Methylenedioxyamphetamine (MDA)
- self-administration and neurotoxicity. Pharmacol. Biochem. Behav. 39:
- 569-574
-
- McBean DE, Sharkey J, Ritchie IM, Kelly PAT (1990) Chronic effects of the
- selective serotoninergic neurotoxin, methylenedioxyamphetamine, upon
- cerebral function. Neuroscience 38: 271-275
-
- Nash JF, Yamamoto BK (1992) Methamphetamine neurotoxicity and striatal
- glutamate release: Comparison to 3,4-methylenedioxymethamphetamine. Brain
- Res. 581: 237-243
-
- O'Hearn E, Battaglia G, DeSouza EB, Kuhar MJ, Molliver ME (1988)
- Methylenedioxyamphetamine (MDA) and methylenedioxymethamphetamine (MDMA)
- cause selective ablation of serotonergic axon terminals in forebrain:
- Immunocytochemical evidence for neurotoxicity. J. Neurosci. 8: 2788-2803
-
- Ricaurte GA, Bryan G, Strauss L, Seiden LS, Schuster CR (1985)
- Hallucenogenic amphetamine selectively destroys brain nerve terminals.
- Science 229: 986-988
-
- Ricaurte GA, Martello AL, Katz JL, Martello MB (1992) Lasting effects of
- 3,4-methylenedioxymethamphetamine (MDMA) on central serotonergic neurons
- in nonhuman primates: Neurochemical observations. J. Pharmacol. Exp.
- Ther. 261: 616-622
-
- Schechter MD (1991) Effect of MDMA neurotoxicity upon its conditioned
- place preference and discrimination. Pharmacol. Biochem. Behav. 38:
- 539-544
-
- Schmidt CJ (1987) Neurotoxicity of the psychedelic amphetamine
- methylenedioxymethamphetamine. J. Pharm. exp. Ther. 240: 1-7
-
- Schmidt CJ, Abbate GM, Black CK, Taylor VL (1990a) Selective
- 5-hydroxytryptamine2 receptor antagonists protect against the
- neurotoxicity of methylenedioxymethamphetamine in rats. J. Pharm. exp.
- Ther. 255: 478-483
-
- Schmidt CJ, Black CK, Abbate GM, Taylor VL (1990)
- Methylenedioxymethamphetamine-induced hyperthermia and neurotoxicity are
- independently mediated by 5-HT2 receptors. Brain Res. 529: 85-90
-
- Schmidt CJ, Black CK, Abbate GM, Taylor VL (1990) Chloral hydrate
- anesthesia antagonizes the neurotoxicity of
- 3,4-methylenedioxymethamphetamine. Eur. J. Pharmacol. 191: 213-216
-
- Schmidt CJ, Black CK, Taylor VL (1990) Antagonism of the neurotoxicity
- due to a single administration of methylenedioxymethamphetamine. Eur. J.
- Pharmacol. 181: 59-70
-
- Schmidt CJ, Taylor VL, Abbate GM, Nieduzak TR (1991) 5-HT2 antagonists
- stereoselectively prevent the neurotoxicity of
- 3,4-methylenedioxymethamphetamine by blocking the acute stimulation of
- dopamine synthesis: Reversal by L-dopa. J. Pharm. exp. Ther. 25 6:
- 230-235
-
- Wilson MA, Ricaurte GA, Molliver ME (1989) Distinct morphologic classes of
- serotonergic axons in primates exhibit differential vulnerability to the
- psychotropic drug 3,4-methylenedioxymethamphetamine. Neuroscience 28:
- 121-138
-
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-