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- Date: Fri, 20 Nov 1992 18:02:00 EDT
- Sender: Psychology Graduate Students Discussion Group List
- <PSYCGRAD@UOTTAWA.BITNET>
- From: KMORGAN@WHEATNMA.BITNET
- Subject: Re: Help with Hippocampi
- Lines: 21
-
- Previously I reported some data that I thought was not yet published on
- hippocampal damage in response to prenatal stress. My Wisconsin
- colleague just sent me the publication in which these data were
- presented:
-
- Uno, H., Lohmiller, L., Thieme, C., Kemnitz, J.W., Engel, M.J.,
- Roecker, E.B. and Farrell, P.M. (1990). Brain damage induced by
- prenatal exposure to dexamethasone in fetal rhesus macaques. I.
- Hippocampus. Developmental Brain Research 53: 157-167
-
- In brief, the offspring of mothers who had been given a single
- clinical doses of dexamethasone mid-gestation had a decreased number of
- pyramidal neurons in the hippocampal CA regions, decreased number of
- granualr neurons in the dentate gyrus, and degeneratioin of neuronal
- perikarya and dendrites. Also, axodendritic synaptic terminals of the
- mossy fibers of the CA3 region showed pronounced degeneration.
-
- WOW! Eric, this is the end (and beginning) of the story!
-
- --Kathy Morgan
- kmorgan@wheatnma.bitnet
-