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- Newsgroups: alt.drugs
- Path: sparky!uunet!convex!darwin.sura.net!spool.mu.edu!umn.edu!csus.edu!netcom.com!rcain
- From: rcain@netcom.com (Robert Cain)
- Subject: Re: Physiological Effects of LSD
- Message-ID: <1992Nov17.074545.17125@netcom.com>
- Organization: Netcom - Online Communication Services (408 241-9760 guest)
- References: <BxtpJx.B76@uxa.ecn.bgu.edu>
- Distribution: alt.drugs
- Date: Tue, 17 Nov 1992 07:45:45 GMT
- Lines: 32
-
- muwjt@uxa.ecn.bgu.edu (William J. Taney) writes:
- :
- : >Ohmygod. Thank you for playing, but...no. First, Serotonin is NOT
- : >'the inhibitor substance' in the brain. Serotonin's effect is mimicked
- : >in CERTAIN parts of the brain >BY< LSD. LSD does not attach itself to
- : >Serotonin. It is an agonist. That means it acts like Serotonin. There
- : >are 5 types of Serotonin receptor in the brain. LSD will interact with
- : >ONE of them. The effect is felt predominantly in the limbic system, and
- : >in certain association areas (tempoparietal, for one).
- :
- : Does anyone know what kind of interaction LSD would have with drugs that
- : are intended to effect seroronin activity such as PROZAC (Flouroextine I
- : think).
- :
-
- The anti-depressant bupropion (Wellbutrin) whose action is poorly
- understood and described as, "a weak blocker of the neuronal uptake
- of serotonin and norepinepherine which also inhibits the neuronal re-
- uptake of dopamine" has a very signifigant effect of nearly blocking
- the effects of LSD if not discontinued for two days prior to tripping.
- This is a personal observation and has been consistant under
- experimentation.
-
- Bob
- --
- Bob Cain rcain@netcom.com 408-358-2007
-
- "There are some strings. They're just not attached."
- Victoria Roberts
-
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- PGP 1.0 or 2.0 public key available on request.
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