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- Newsgroups: alt.drugs
- Path: sparky!uunet!cis.ohio-state.edu!pacific.mps.ohio-state.edu!linac!uchinews!ellis!bagg
- From: bagg@ellis.uchicago.edu (matthew john baggott)
- Subject: Re: Psychedelic effects of Flenfluramine
- Message-ID: <1992Nov17.043330.9377@midway.uchicago.edu>
- Sender: news@uchinews.uchicago.edu (News System)
- Reply-To: bagg@midway.uchicago.edu
- Organization: University of Chicago Computing Organizations
- References: <1992Nov13.203342.28823@mnemosyne.cs.du.edu>
- Date: Tue, 17 Nov 1992 04:33:30 GMT
- Lines: 22
-
- In article <1992Nov13.203342.28823@mnemosyne.cs.du.edu> ahead@nyx.cs.du.edu (Adam Head) writes:
-
- >This form of the drug is a mixture of S and L isomers. Nichol's
- >rats have suggested the S isomer to have MDMA-like effects as well
- >as similar neurotoxicity (not proved to be harmful to humans).
-
- Nichols concluded long ago that fenfluramine was a false positive.
- Although it substitutes for MDMA in rat discrimination studies, it
- does not have entactogenic effects in humans. In fact Dr. Nichols
- told me that he's come to a bit of a dead end trying to use
- the drug discrimination paradigm to identify new entactogens.
- Apparently, the non-neurotoxic substances (such as MDAI) which the
- rats considered MDMA-like have proven to be non-entactogenic in
- humans. So he's basically without an animal model for the
- entactogenic effect. He's recently been involved in EEG work,
- partially in attempt to identify some unique characteristic of
- entactogens.
-
- --Matt B.
-
-
-
-