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OCR: Summary and Review Tools Mechanism Review: Substitution versus Elimination and E Priman substrate Tertiary substrate Back side attack of Nu: with respect to LG Carbocation intermediate Strong/polarizable unhindered nucleophile Weal nucleophile/base (e solvent) Favored Inversion Concerted Bimolecular b of bond in polar rate aprotic forming/bond determining solvent step breaking Protic Removal Racemization Unimolecular solvent of in assists SNl -hydrogen if rate-determining ionization F of LG step f stereochemistry Low temperature SN1/ high temperature F2 Nu/B LG Nu/B LG 52 and E2 Secondary or primary substrate Tertian or secondary substrate Strong unhinderec base/nucler Concerted ant -coplanar leads to S2 Strong hindered base/nucl Bimolecular in rate-determining sten Low temperature tempera ...