DEF: A physiologic function occurring at the molecular level. This type has
one child in the network, 'Genetic Function'. Metathesaurus examples include
"Electron Transport", "Glycolysis", and "Binding, Competitive".
STY: Molecular Sequence
DEF: A broad type for grouping the collected sequences of amino acids,
carbohydrates, and nucleotide sequences. Descriptions of these sequences are
generally reported in the published literature and/or are deposited in and
maintained by databanks such as GenBank, European Molecular Biology Laboratory
(EMBL), National Biomedical Research Foundation (NBRF), or other sequence
repositories. The children of this type in the network are 'Nucleotide
Sequence', 'Amino Acid Sequence', and 'Carbohydrate Sequence'.
STY: Natural Phenomenon or Process
DEF: A phenomenon or process that occurs irrespective of the activities of
human beings. This type has one child in the network, 'Biologic Function'.
Metathesaurus examples include "Lightning", "Air Movements",
"Sunlight", "Biological Phenomena", and "Corrosion".
STY: Neuroreactive Substance or Biogenic Amine
DEF: A biologic factor whose activities affect or play a role in the
functioning of the nervous system. Included here are catecholamines,
neuroregulators, neurophysins, etc. Metathesaurus examples include
"Catecholamine", "Tryptamines", and "Neurotensin".
STY: Nucleic Acid, Nucleoside, or Nucleotide
DEF: A complex compound of high molecular weight occurring in living cells.
These are basically of two types, ribonucleic (RNA) and deoxyribo-nucleic
(DNA) acids, both of which consist of nucleotides (nucleoside phosphates
linked together by phosphate bridges). Metathesaurus examples include
"Adenosine", "Dibutyryl Cyclic AMP", "Deoxyadenosines", and "Nicotinamide
Mononucleotide".
STY: Nucleotide Sequence
DEF: The sequence of purines and pyrimidines in nucleic acids and
polynucleotides. Included here are nucleotide-rich regions, conserved
sequence, and DNA transforming region. Metathesaurus examples include "AT
Rich Region", "Base Sequence", "Direct Repeat", and "Exons".
STY: Occupation or Discipline
DEF: A vocation, academic discipline, or field of study, or a subpart of an
occupation or discipline. If the term refers to the individuals who have the
vocation, the type 'Professional or Occupational Group' is assigned. This type
has one child in the network, 'Biomedical Occupation or Discipline'.
Metathesaurus examples include "Anthropology", "Ecology", "Linguistics", "Air
Microbiology", and "Craniology".
STY: Occupational Activity
DEF: An activity carried out as part of an occupation or job. The children of
this type in the network are 'Health Care Activity', 'Research Activity',
'Governmental or Regulatory Activity', and 'Educational Activity'.
Metathesaurus examples include "Financial Management", "Collective Bargaining",
"Commerce", and "Book Classification".
STY: Organ or Tissue Function
DEF: A physiologic function of a particular organ, organ system, or tissue.
Metathesaurus examples include "Osteogenesis", "Tooth Calcification", and
"Renal Circulation".
STY: Organic Chemical
DEF: The general class of carbon-containing compounds, usually based on carbon
chains or rings, and also containing hydrogen (hydrocarbons), with or without
nitrogen, oxygen, or other elements. The bonding between elements is generally
covalent. The children of this type in the network are 'Steroid',
'Eicosanoid', 'Lactam', 'Alkaloid', 'Nucleic Acid, Nucleoside, or Nucleotide',
'Organophosphorus Compound', 'Amino Acid, Peptide, or Protein', 'Carbohydrate',
and 'Lipid'. Metathesaurus examples include "Busulfan", "Carotene",
"Trinitrobenzene", and "Metanephrine".
STY: Organism Attribute
DEF: A property of the organism or its major parts. If the term refers to an
attribute found only in non-humans, the Non-Human flag is assigned as well.
Metathesaurus examples include "Body Weight", "Body Temperature",
"Ambidexterity", and "Eye Color".
STY: Organism Function
DEF: A physiologic function of the organism as a whole, of multiple organ
systems, or of multiple organs or tissues. This type has one child in the
network, 'Mental Process'. Metathesaurus examples include "Growth", "Sleep",
"Hibernation", and "Homeostasis".
STY: Organism
DEF: Generally, a living individual, including all plants and animals. The
children of this type in the network are 'Plant', 'Fungus', 'Virus',
'Rickettsia or Chlamydia', 'Bacterium', and 'Animal'. Metathesaurus examples
include "Plankton", "Homozygote", and "Radiation Chimera".
STY: Organization
DEF: The result of uniting for a common purpose or function. The continued
existence of an organization is not dependent on any of its members, its
location, or particular facility. Components or subparts of organizations are
also included here. The children of this type in the network are 'Health Care
Related Organization', 'Professional Society', and 'Self-help or Relief
Organization'. Metathesaurus examples include "Universities", "United
Nations", "United States Environmental Protection Agency", "European Economic
Community", and "Labor Unions".
STY: Organophosphorus Compound
DEF: An organic compound containing phosphorus as a constituent. Included here
are organic phosphinic, phosphonic and phosphoric acid derivatives and their
thiophosphorus counterparts. Excluded are phospholipids and sugar phosphates.
Metathesaurus examples include "Phosphonoacetic Acid", "Phosphoric Acid
Esters", "Diphosphonates", and "Thiamine Triphosphate".
STY: Pathologic Function
DEF: A disordered process, activity, or state of the organism as a whole, of a
body system or systems, or of multiple organs or tissues. Included here are
normal responses to a negative stimulus as well as patholologic conditions or
states that are less specific than a disease. Pathologic functions frequently
have systemic effects. The children of this type in the network are 'Disease
or Syndrome', 'Cell or Molecular Dysfunction', and 'Experimental Model of
Disease'. Metathesaurus examples include "Shock", "Infarction", "Cerebral
Anoxia", "Inflammation", "Anaphylaxis", and "Acid-Base Imbalance".
STY: Patient or Disabled Group
DEF: An individual or individuals classified according to a disability,
disease, condition or treatment. Metathesaurus examples include "Amputees",
"Child, Institutionalized", and "Inpatients".
STY: Pharmacologic Substance
DEF: A substance used in the treatment, diagnosis, prevention, or analysis of
normal and abnormal body function. This includes substances that occur
naturally in the body and are administered therapeutically. Metathesaurus
examples include "Codeine", "Antipruritics", "Ampicillin", "Cardiovascular
Agents", "Insulin", and "Ganglionic Blockaders".
STY: Phenomenon or Process
DEF: A process or state which occurs naturally or as a result of an activity.
The children of this type in the network are 'Human-caused Phenomenon or
Process', 'Natural Phenomenon or Process', and 'Injury or Poisoning'.
Metathesaurus examples include "Disasters", "Famine", and "Noise".
STY: Physical Object
DEF: An object perceptible to the sense of vision or touch. The children of
this type in the network are 'Organism', 'Anatomical Structure', 'Manufactured
Object', and 'Substance'.
STY: Physiologic Function
DEF: A normal process, activity, or state of the body. The children of this
type in the network are 'Organism Function', 'Organ or Tissue Function', 'Cell
Function', and 'Molecular Function'.
STY: Plant
DEF: An organism having cellulose cell walls, growing by synthesis of inorganic
substances, generally distinguished by the presence of chlorophyll, and lacking
the power of locomotion. Plant parts are included here as well. This type has
one child in the network, 'Alga'. Metathesaurus examples include "Potatoes",
"Pollen", and "Vegetables".
STY: Population Group
DEF: An indivdual or individuals classified according to their sex, racial
origin, religion, common place of living, financial or social status, or some
other cultural or behavioral attribute. Metathesaurus examples include
"Asian Americans", "Ethnic Groups", "Homeless Persons", and "Low-Income
Population".
STY: Professional Society
DEF: An organization uniting those who have a common vocation or who are
involved with a common field of study. Metathesaurus examples include
"American Medical Association", "Library Associations", and "International
Council of Nurses".
STY: Professional or Occupational Group
DEF: An individual or individuals classified according to their vocation.
Metathesaurus examples include "Zoologist", "Physicians", "Hospital
Volunteers", "Clergy", "Military Personnel", and "Demographers".
STY: Prostaglandin
DEF: A member of the group of physiologically active compounds derived from
arachidonic acid. Members of the group play major roles in the reproductive
process, smooth muscle stimulation, blood pressure levels, inflammation, etc.
Included here are prostacyclins, thromboxanes, and leukotrienes. Metathesaurus
examples include "Alprostadil", "Prostaglandins F", "Thromboxane A2", and
"Rioprostil".
STY: Qualitative Concept
DEF: A concept which is an assessment of some quality, rather than a direct
measurement. Metathesaurus examples include "Clinical Competence", "Quality
of Health Care", "Abuse of Health Services", and "Consumer Satisfaction".
STY: Quantitative Concept
DEF: A concept which involves the dimensions, quantity or capacity of something
using some unit of measure, or which involves the quantitative comparison of
entities. Metathesaurus examples include "Metric System", "Body Height",
"Age Distribution", and "Secretory Rate".
STY: Regulation or Law
DEF: An intellectual product resulting from legislative or regulatory activity.
Metathesaurus examples include "Building Codes", "Criminal Law", "Health
Planning Guidelines", and "Security Measures".
STY: Reptile
DEF: A cold-blooded vertebrate having an external covering of scales or horny
plates. Reptiles breathe by means of lungs and are generally egg-laying.
Metathesaurus examples include "Lizards", "Snakes", "Turtles", and "Iguanas".
STY: Research Activity
DEF: An activity carried out as part of research or experimentation. This type
has one child in the network, 'Molecular Biology Research Technique'.
Metathesaurus examples include "Study Design", "Animal Experimentation",
"Biomedical Research", and "Cluster Analysis".
STY: Research Device
DEF: A manufactured object used primarily in carrying out scientific research
or experimentation. Metathesaurus examples include "Questionnaires",
"Atmosphere Exposure Chambers", and "Cell-Free System".
STY: Rickettsia or Chlamydia
DEF: An organism intermediate in size and complexity between a virus and a
bacterium, and which is parasitic within the cells of insects and ticks.
Included here are all the chlamydias, also called "PLT" for psittacosis-
lymphogranuloma venereum-trachoma. Metathesaurus examples include "Anaplasma",
"Bartonella", and "Chlamydia trachomatis".
STY: Self-help or Relief Organization
DEF: An organization whose purpose and function is to provide assistance to the
needy or to offer support to those sharing similar problems. Metathesaurus
examples include "Alcoholics Anonymous", "Red Cross", "Charities", and
"Tuberculosis Societies".
STY: Sign or Symptom
DEF: An observable manifestation of a disease or condition based on clinical
judgment, or a manifestation of a disease or condition which is experienced by
the patient and reported as a subjective observation. Metathesaurus examples
include "Pallor", "Body Weight Changes", "Echolalia", "Hyperventilation",
"Pain", "Toothache", "Nausea", and "Cough".
STY: Social Behavior
DEF: Behavior that is a direct result or function of the interaction of humans
or animals with their fellows. Metathesaurus examples include "Interpersonal
Relations", "Social Conformity", "Acculturation", and "Communication".
STY: Spatial Concept
DEF: A location, region, or space, generally having definite boundaries. The
children of this type in the network are 'Body Space or Junction', 'Body
Location or Region', 'Molecular Sequence', and 'Geographic Area'.
STY: Steroid
DEF: One of a group of polycyclic, 17-carbon-atom, fused-ring compounds
occurring both in natural and synthetic forms. Included here are naturally
occurring and synthetic steroids, bufanolides, cardanolides, homosteroids,
norsteroids, and secosteroids. Metathesaurus examples include "Bufanolides",
"Norandrostanes", "17-Hydroxycorticosteroids", and "Prednisone".
STY: Substance
DEF: A material with definite or fairly definite chemical composition. The
children of this type in the network are 'Chemical', 'Body Substance', and
'Food'. Metathesaurus examples include "Charcoal", "Foreign Bodies", "Air",
"Fossils", and "Electrons".
STY: Temporal Concept
DEF: A concept which pertains to time or duration. Metathesaurus examples
include "Half-Life", "Postoperative Period", "Puerperium", "Birth Intervals",
and "Postimplantation Phase".
STY: Therapeutic or Preventive Procedure
DEF: A procedure, method, or technique designed to prevent a disease or a
disorder, or to improve physical function, or used in the process of treating
a disease or injury. Metathesaurus examples include "Cesarean Section",
"Counseling", "Vaccine Therapy", and "Cochlear Implant".
STY: Tissue
DEF: An aggregation of similarly specialized cells and the associated
intercellular substance. Tissues are relatively non-localized in comparison
to body parts, organs or organ components. Metathesaurus examples include
"Cartilage", "Epidermis", "Basophilic muscle fibers", and "Endothelium".
STY: Vertebrate
DEF: An animal which has a spinal column. The children of this type in the
network are 'Amphibian', 'Bird', 'Fish', 'Reptile', and 'Mammal'.
STY: Virus
DEF: An organism consisting of a core of a single nucleic acid enclosed in a
protective coat of protein. A virus may replicate only inside a host living
cell. A virus exhibits some but not all of the usual characteristics of living
things. Metathesaurus examples include "Parvoviridae", "Foot-and-Mouth Disease
Virus", and "Echovirus 6".
STY: Vitamin
DEF: A substance, usually an organic chemical complex, present in natural
products or made synthetically, which is essential in the diet of man or other
higher animals. Included here are vitamin precursors and provitamins.
Metathesaurus examples include "Vitamin A", "Ascorbic Acid", "Biotin",
"Riboflavin", and "25-Hydroxyvitamin D 2".
STY|T001|Organism|A1.1|Generally, a living individual, including all plants and animals. The children of this type in the network are 'Plant', 'Fungus', 'Virus', 'Rickettsia or Chlamydia', 'Bacterium', and 'Animal'. Metathesaurus examples include "Plankton", "Homozygote", and "Radiation Chimera".|||
STY|T002|Plant|A1.1.1|An organism having cellulose cell walls, growing by synthesis of inorganic substances, generally distinguished by the presence of chlorophyll, and lacking the power of locomotion. Plant parts are included here as well. This type has one child in the network, 'Alga'. Metathesaurus examples include "Potatoes", "Pollen", and "Vegetables".|||
STY|T003|Alga|A1.1.1.1|A chiefly aquatic plant that contains chlorophyll, but does not form embryos during development and lacks vascular tissue. Metathesaurus examples include "Chlorella", "Laminaria", "Seaweed", and "Anabaena".|||
STY|T004|Fungus|A1.1.2|A eukaryotic organism characterized by the absence of chlorophyll and the presence of a rigid cell wall. Included here are both slime molds and true fungi such as yeasts, molds, mildews, and mushrooms. Metathesaurus examples include "Blastomyces", "Neurospora", "Aspergillus clavatus", and "Helminthosporium".|||
STY|T005|Virus|A1.1.3|An organism consisting of a core of a single nucleic acid enclosed in a protective coat of protein. A virus may replicate only inside a host living cell. A virus exhibits some but not all of the usual characteristics of living things. Metathesaurus examples include "Parvoviridae", "Foot-and-Mouth Disease Virus", and "Echovirus 6".|||
STY|T006|Rickettsia or Chlamydia|A1.1.4|An organism intermediate in size and complexity between a virus and a bacterium, and which is parasitic within the cells of insects and ticks. Included here are all the chlamydias, also called "PLT" for psittacosis- lymphogranuloma venereum-trachoma. Metathesaurus examples include "Anaplasma", "Bartonella", and "Chlamydia trachomatis".|||
RL|T141|carries_out|CC.2|Executes a function or performs a procedure or activity. This includes transacts, operates on, handles, and executes.|CO|carried_out_by|
RL|T142|interacts_with|CC.3|Acts, functions, or operates together with.|IW|interacts_with|
RL|T143|practices|CC.4|Performs habitually or customarily.|PA|practiced_by|
RL|T144|produces|CC.5|Brings forth, generates or creates. This includes yields, secretes, emits, biosynthesizes, generates, releases, discharges, and creates.|PS|produced_by|
Activity|isa|Event|D|
Amphibian|isa|Vertebrate|D|
Animal|isa|Organism|D|
Biologic Function|isa|Natural Phenomenon or Process|D|
Body Location or Region|isa|Spatial Concept|D|
Diagnostic Procedure|isa|Health Care Activity|D|
Finding|associated_with|Pathologic Function|D|
Group|exhibits|Behavior|D|
Injury or Poisoning|complicates|Pathologic Function|D|