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1994-01-17
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$Unique_ID{BRK03782}
$Pretitle{}
$Title{Gottron's Syndrome}
$Subject{Gottron's Syndrome Familial Acrogeria Familial Acromicria}
$Volume{}
$Log{}
Copyright (C) 1986, 1988 National Organization for Rare Disorders,
Inc.
128:
Gottron's Syndrome
** IMPORTANT **
It is possible that the main title of the article (Gottron's Syndrome) is
not the name you expected. Please check the SYNONYM listing to find the
alternate names and disorder subdivisions covered by this article.
Synonyms
Familial Acrogeria
Familial Acromicria
General Discussion
** REMINDER **
The information contained in the Rare Disease Database is provided for
educational purposes only. It should not be used for diagnostic or treatment
purposes. If you wish to obtain more information about this disorder, please
contact your personal physician and/or the agencies listed in the "Resources"
section.
Gottron's syndrome is a mild form of progeria, or premature ageing, in
which the extremities remain unusually small. The disorder is familial. The
prognosis for a normal life is good.
Symptoms
The hands and feet of patients with Gottron's syndrome remain small into
adulthood, with thin, parchment-like skin, so they seem much older than the
chronological age. There is little subcutaneous fat in neither the
extremities nor on the chest so the veins on the chest are prominent.
Causes
Gottron's syndrome appears to be familial, but the inheritance pattern is not
understood.
Affected Population
Gottron's Syndrome affects males and females equally.
Related Disorders
Hutchinson-Gilford syndrome is a more severe form of progeria (premature
ageing) affecting children. Werner syndrome, another form of progeria,
affects adults. (For more information on these disorders, choose progeria,
Werner, and Hutchinson-Gilford as your search terms in the Rare Disease
Database.)
Therapies: Standard
Treatment for Gottron's Syndrome is symptomatic and supportive.
Therapies: Investigational
This disease entry is based upon medical information available through March
1987. Since NORD's resources are limited, it is not possible to keep every
entry in the Rare Disease Database completely current and accurate. Please
check with the agencies listed in the Resources section for the most current
information about this disorder.
Resources
For more information on Gottron's Syndrome, please contact:
National Organization for Rare Disorders (NORD)
P.O. Box 8923
New Fairfield, CT 06812-1783
(203) 746-6518
The Progeria International Registry (PIR)
New York State Institute for Basic Research in Developmental Disabilities
1050 Forest Hill Road
Staten Island, NY 10314
(718) 494-0600
Progeria Foundation
3 Styvesant Oval, 9A
New York, NY 10009
Sunshine Foundation
4010 Levick St.
Philadelphia, PA 19135
(The Sunshine Foundation raises funds to bring all children with Progeria
together each year so that medical researchers can study their progress while
the children socialize in a vacation atmosphere.)
NIH/National Institute of Child Health and Human Development
9000 Rockville Pike
Bethesda, MD 20892
(301) 496-5133
For information on genetics and genetic counseling referrals, please
contact:
March of Dimes Birth Defects Foundation
1275 Mamaroneck Avenue
White Plains, NY 10605
(914) 428-7100
Alliance of Genetic Support Groups
35 Wisconsin Circle, Suite 440
Chevy Chase, MD 20815
(800) 336-GENE
(301) 652-5553
References
CECIL TEXTBOOK OF MEDICINE, 18th ed.: James B. Wyngaarden, and Lloyd H.
Smith, Jr., Eds.: W. B. Saunders Co., 1988. P. 2035.