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$Unique_ID{BRK03537}
$Pretitle{}
$Title{Bowenoid Papulosis}
$Subject{Bowenoid Papulosis BP Bowen's Disease Condyloma Lichen Planus}
$Volume{}
$Log{}
Copyright (C) 1992 National Organization for Rare Disorders, Inc.
925:
Bowenoid Papulosis
** IMPORTANT **
It is possible that the main title of the article (Bowenoid Papulosis) is
not the name you expected. Please check the SYNONYMS listing to find the
alternate name and disorder subdivisions covered by this article.
Synonyms
BP
Information on the following diseases can be found in the Related
Disorders section of this report:
Bowen's Disease
Condyloma
Lichen Planus
General Discussion
** REMINDER **
The Information contained in the Rare Disease Database is provided for
educational purposes only. It should not be used for diagnostic or treatment
purposes. If you wish to obtain more information about this disorder, please
contact your personal physician and/or the agencies listed in the "Resources"
section of this report.
Bowenoid Papulosis is a rare sexually transmitted disorder thought to be
caused by human papillomavirus type 16. This disorder is characterized by
lesions that are found on the genitals of males and females. The lesions are
reddish brown or violet in color, small, solid, raised and sometimes velvety.
Symptoms
Bowenoid Papulosis is a rare sexually transmitted infection that is
characterized by lesions that are typically found on the genitals. These
lesions may last from two weeks to several years. Females may be affected
inside the vagina, on the clitoris, groin folds, labia major, labia minor
and/or anus. Males may be affected on the glans, shaft and/or foreskin of
the penis as well as the anus. The lesions found in Bowenoid Papulosis are
usually reddish brown or violet in color, small, solid, smooth, raised and
velvety. The lesions on females are usually darker than the lesions on
males.
Many patients with Bowenoid Papulosis often have other types of viral
infections that precede this condition. Herpes simplex, human
papallomavirus, viral warts, and HIV infection have been found in some
patients with this disorder. When viewed under a microscope the Bowenoid
Papulosis tissue structure looks like pre-invasive squamous-cell carcinoma (a
form of cancer cells). In some cases Bowenoid Papulosis has become
malignant.
Causes
Bowenoid Papulosis is a sexually transmitted disorder thought to be caused by
human papillomavirus type 16. Other viruses as well as a suppressed immune
system may also play a role in contracting Bowenoid Papulosis.
Affected Population
Bowenoid Papulosis affects males and females in equal numbers. This disorder
is seen in sexually active adults with the average ages being 30 for males
and 32 for females. However, Bowenoid Papulosis has been found in patients
ranging from ages 3 to 80. It has recently been appearing in increasing
numbers worldwide.
Related Disorders
Symptoms of the following disorders can be similar to those of Bowenoid
Papulosis. Comparisons may be useful for a differential diagnosis:
Bowen's Disease is characterized by a precancerous, slow growing skin
malignancy. The major symptom is a red-brown, scaly or crusted patch on the
skin which resembles psoriasis or dermatitis. It may occur on any part of
the skin or in the mucous membranes. (For more information on this disorder,
choose "Bowen's Disease" as your search term in the Rare Disease Database).
Condyloma is a common infectious venereal disease that is caused by the
human papillomavirus (HPV) and usually transmitted by direct sexual contact.
The warts found in this disorder are small, soft, moist, pink or red
elevations on the skin or mucous membranes of the genitals, mouth, anus or
rectum. Typically the warts form in clusters. (For more information on this
disorder, choose "Condyloma" as your search term in the Rare Disease
Database).
Lichen Planus is a recurrent, itchy, inflammatory eruption of the skin
which is characterized by small, separate, angular spots that may grow
together forming rough scaly patches. It is often accompanied by oral
lesions. Women are most commonly affected by this disorder. The lesions are
most commonly found on the joint surfaces of the wrists and on the legs,
trunk, glands, penis and mucous membrane of the mouth and vagina. (For more
information on this disorder, choose "Lichen Planus" as your search term in
the Rare Disease Database).
Therapies: Standard
Patients with Bowenoid Papulosis should be monitored carefully. In some
cases Bowenoid Papulosis may heal spontaneously (without treatment). Sexual
activity should be limited in order to avoid infecting other people during
the contagious stages of this disorder.
Electrosurgery, cryosurgery (surgery in which the tissue is frozen with
liquid nitrogen), and/or lazer surgery may be used to remove the lesions when
necessary.
In some milder cases the use of 5-Fluorouracil (a topical cream) has been
successful.
Therapies: Investigational
Research on skin disorders is ongoing at major medical universities.
Progress on the understanding of viral infections has increased during recent
years, but there has been little progress in the development of new treatment
for viral diseases.
This disease entry is based upon medical information available through
August 1992. Since NORD's resources are limited, it is not possible to keep
every entry in the Rare Disease Database completely current and accurate.
Please check with the agencies listed in the Resources section for the most
current information about this disorder.
Resources
For more information on Bowenoid Papulosis, please contact:
National Organization for Rare Disorders (NORD)
P.O. Box 8923
New Fairfield, CT 06812-1783
(203) 746-6518
American Social Health Association
100 Capitola Dr., Suite 200
Research Triangle Park, NC 27713
(919) 361-8400
Council for Sex Information and Education
444 Lincoln Blvd., Suite 107
Venice, CA 90291
National Sexually Transmitted Diseases Hotline
(800) 227-8922
NIH/National Institute of Allergy and Infectious Diseases (NIAID)
9000 Rockville Pike
Bethesda, MD 20892
(301) 496-5717
Centers for Disease Control (CDC)
1600 Clifton Road , NE
Atlanta, GA 30333
(404) 639-3534
References
CLINICAL DERMATOLOGY, 2nd Ed.; Thomas P. Habif, M.D., Editor: The C.V. Mosby
Company, 1990. Pp. 246.
BOWENOID PAPULOSIS: T.T. Rogozinski, et al.; Am Fam Physician (July,
1988, issue 38(1)). Pp. 161-4.
BOWENOID PAPULOSIS. DEMONSTRATION OF HUMAN PAPILLOMAVIRUS (HPV) WITH
ANTI-HPV IMMUNE SERUM: G.Y. Guillet, et al.; Arch Dermatol (April, 1984,
issue 120(4)). Pp. 514-6.
BOWENOID PAPULOSIS OF THE GENITALIA: T.R. Wade et al.; Arch Dermatol
(March, 1979, issue 115(3)). Pp. 306-8.
BOWENOID PAPULOSIS. PRESENCE OF HUMAN PAPILLOMAVIRUS (HPV) STRUCTURAL
ANTIGENS AND OF HPV 16-RELATED DNA SEQUENCES: G. Gross et al.; Arch Dermol
(July, 1985, issue 121(7)). Pp. 858-63.
BOWENOID PAPULOSIS: J.W. LaVoo; Dis Colon Rectum (January, 1987, issue
30(1)). Pp. 62-4.
BOWENOID PAPULOSIS OF THE MALE AND FEMALE GENETALIA: S. Obalek et al.; J
Am Acad Dermatol (March, 1986, issue 14(3)). Pp. 433-44.