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- $Unique_ID{BRK03236}
- $Pretitle{}
- $Title{metronidazole}
- $Subject{Femazole Major Searle Flagyl Metezole Glenwood Curatab MetroGel
- Metryl Lemmon Ortho Protostat Satric Savage Antibiotic antiparasitic
- metronidazole infections vagina urinary lower respiratory tract bones
- joints intestinal tract skin acne rosacea bacteria parasites}
- $Volume{}
- $Log{}
-
- Copyright (C) 1993 Publications International, Ltd.
-
-
- metronidazole
- ------------------------------------------------------------------------------
-
- BRAND NAMES (Manufacturers)
-
- Femazole (Major)
- Flagyl (Searle)
- Metezole (Glenwood)
- MetroGel (Curatab)
- metronidazole (various manufacturers)
- Metryl (Lemmon)
- Protostat (Ortho)
- Satric (Savage)
-
- TYPE OF DRUG
-
- Antibiotic and antiparasitic
-
- INGREDIENT
-
- metronidazole
-
- DOSAGE FORMS
-
- Tablets (250 mg and 500 mg)
- Topical gel (0.75%)
-
- STORAGE
-
- Metronidazole should be stored at room temperature in a tightly closed,
- light-resistant container. The topical gel form of this medication should
- never be frozen.
-
- USES
-
- Metronidazole is used to treat a wide variety of infections, including
- infections of the vagina, urinary tract, lower respiratory tract, bones,
- joints, intestinal tract, and skin. It is also used topically to treat acne
- rosacea. It acts by killing bacteria or parasites.
-
- TREATMENT
-
- In order to avoid stomach irritation, you should take metronidazole with
- food or with a full glass of water or milk (unless your doctor directs you to
- do otherwise).
- Metronidazole works best when the level of medicine in your bloodstream
- is kept constant. It is best, therefore, to take the doses at evenly spaced
- intervals day and night. For example, if you are to take three doses a day,
- the doses should be spaced eight hours apart.
- Try not to miss any doses of this medication. If you do miss a dose,
- take the missed dose as soon as possible, unless it is almost time for the
- next dose. In that case, do not take the missed dose at all; just return to
- your regular dosing schedule. Do not double the next dose.
- It is important to continue to take this medication for the entire time
- prescribed by your doctor (usually seven to 14 days), even if the symptoms
- disappear before the end of that period. If you stop taking the drug too
- soon, resistant bacteria and parasites are given a chance to continue growing,
- and the infection could recur.
-
- SIDE EFFECTS
-
- Minor.
-
- Abdominal cramps, constipation, decreased sexual interest, diarrhea,
- dizziness, dry mouth, headache, insomnia, irritability, joint pain, loss of
- appetite, metallic taste in the mouth, nasal congestion, nausea, restlessness,
- or vomiting. These side effects should disappear as your body adjusts to the
- medication.
- To relieve constipation, increase the amount of fiber in your diet (fresh
- fruits and vegetables, salads, bran, and whole-grain breads), exercise, and
- drink more water (unless your doctor directs you to do otherwise).
- If you feel dizzy, sit or lie down for a while.
- To relieve mouth dryness, chew sugarless gum or suck on ice chips or a
- piece of hard candy.
-
- Major.
-
- Tell your doctor about any side effects that are persistent or
- particularly bothersome. IT IS ESPECIALLY IMPORTANT TO TELL YOUR DOCTOR about
- confusion, convulsions, flushing, hives, itching, joint pain, loss of bladder
- control, mouth sores, numbness or tingling in the fingers or toes, rash, sense
- of pressure inside your abdomen, unexplained sore throat and fever, or unusual
- weakness. Also, if your symptoms of infection seem to be getting worse rather
- than improving, you should contact your doctor.
-
- INTERACTIONS
-
- Metronidazole interacts with several other types of medications:
- 1. Concurrent use of alcohol and metronidazole can lead to a severe
- reaction (abdominal cramps, nausea, vomiting, headache, and flushing), the
- severity of which is dependent upon the amount of alcohol ingested.
- 2. Concurrent use of disulfiram and metronidazole can lead to confusion.
- 3. The effects of oral anticoagulants (blood thinners, such as warfarin)
- may be increased by metronidazole, which can lead to bleeding complications.
- 4. Barbiturates can increase the breakdown of metronidazole, which can
- decrease its effectiveness.
- 5. Cimetidine can decrease the breakdown of metronidazole, which can
- increase the chance of side effects.
- BE SURE TO TELL YOUR DOCTOR about any medications you are currently
- taking, especially any of those listed above.
-
- WARNINGS
-
- * Tell your doctor about unusual or allergic reactions you have had to
- any medications.
- * Before starting to take this medication, be sure to tell your doctor if
- you now have or if you have ever had blood disorders, a central nervous system
- (brain or spinal cord) disease, or liver disease.
- * When metronidazole is used to treat a vaginal infection, sexual
- partners should receive concurrent therapy in order to prevent reinfection.
- In addition, sexual intercourse should be avoided or condoms should be used
- until treatment is completed.
- * This medication has been prescribed for your current infection only.
- Another infection later on, or one that someone else has, may require
- different drug therapy. Therefore, you should not give your medicine to other
- people or use it for other infections, unless your doctor specifically directs
- you to do so.
- * If this drug makes you dizzy, avoid tasks that require alertness, such
- as driving a car or operating potentially dangerous machinery.
- * Before having surgery or any other medical or dental treatment, be sure
- to tell your doctor or dentist that you are taking this medication.
- * Be sure to tell your doctor if you are pregnant. Although
- metronidazole appears to be safe, it does cross the placenta, and extensive
- studies in pregnant women have not been conducted. Also, tell your doctor if
- you are breast-feeding an infant. Metronidazole passes into breast milk.
-
- ----------------
-
- The material contained here is "FOR INFORMATION ONLY" and should not replace
- the counsel and advice of your personal physician. Promptly consulting your
- doctor is the best path to a quick and successful resolution of any medical
- problem.
-