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- $Unique_ID{BRK03227}
- $Pretitle{}
- $Title{methyclothiazide}
- $Subject{Aquatensen Wallace Enduron Abbott Ethon Major antihypertensive
- Diuretic methyclothiazide high blood pressure fluid accumulation heart failure
- cirrhosis liver kidney disease elimination salt water kidneys}
- $Volume{}
- $Log{}
-
- Copyright (C) 1993 Publications International, Ltd.
-
-
- methyclothiazide
- ------------------------------------------------------------------------------
-
- BRAND NAMES (Manufacturers)
-
- Aquatensen (Wallace)
- Enduron (Abbott)
- Ethon (Major)
- methyclothiazide (various manufacturers)
-
- TYPE OF DRUG
-
- Diuretic and antihypertensive
-
- INGREDIENT
-
- methyclothiazide
-
- DOSAGE FORM
-
- Tablets (2.5 mg and 5 mg)
-
- STORAGE
-
- This medication should be stored at room temperature in a tightly closed
- container.
-
- USES
-
- Methyclothiazide is prescribed to treat high blood pressure. It is also
- used to reduce fluid accumulation in the body caused by certain conditions,
- such as heart failure, cirrhosis of the liver, and kidney disease, and by the
- long-term use of some medications. This medication reduces fluid accumulation
- by increasing the elimination of salt and water through the kidneys.
-
- TREATMENT
-
- This medication can be taken with a glass of milk or with a meal to
- decrease stomach irritation (unless your doctor directs you to do otherwise).
- Try to take it at the same time every day. Avoid taking a dose after 6:00
- P.M.; otherwise, you may have to get up during the night to urinate.
- If you miss a dose of this medication, take the missed dose as soon as
- possible, unless it is almost time for the next dose. In that case, do not
- take the missed dose at all; just wait until the next scheduled dose. Do not
- double the dose.
- This medication does not cure high blood pressure, but it will help to
- control the condition as long as you continue to take it.
-
- SIDE EFFECTS
-
- Minor.
-
- Constipation, cramps, diarrhea, dizziness, drowsiness, headache,
- heartburn, loss of appetite, restlessness, or upset stomach. As your body
- adjusts to the medication, these side effects should disappear.
- This medication can cause increased sensitivity to sunlight. It is,
- therefore, important to avoid prolonged exposure to sunlight and sunlamps.
- Wear protective clothing, and use an effective sunscreen.
- To relieve constipation, increase the amount of fiber in your diet (fresh
- fruits and vegetables, salads, bran, and whole-grain breads) and exercise more
- (unless your doctor directs you to do otherwise).
- To avoid dizziness or light-headedness when you stand, contract and relax
- the muscles of your legs for a few moments before rising. Do this by pushing
- one foot against the floor while raising the other foot slightly, alternating
- feet so that you are "pumping" your legs in a pedaling motion.
-
- Major.
-
- Tell your doctor about any side effects that are persistent or
- particularly bothersome. IT IS ESPECIALLY IMPORTANT TO TELL YOUR DOCTOR about
- blurred vision, confusion, difficulty in breathing, dry mouth, excessive
- thirst, excessive weakness, fainting, fever, itching, joint pain, mood
- changes, muscle pain or spasms, nausea, palpitations, skin rash, sore throat,
- tingling in the fingers or toes, unusual bleeding or bruising, vomiting, or
- yellowing of the eyes or skin.
-
- INTERACTIONS
-
- Methyclothiazide interacts with several other types of medications:
- 1. It may decrease the effectiveness of oral anticoagulants, antigout
- medications, insulin, oral antidiabetic medicines, and methenamine.
- 2. Fenfluramine can increase the blood-pressure-lowering effects of
- methyclothiazide (which can be dangerous to your health).
- 3. Indomethacin can decrease the blood-pressure-lowering effects of
- methyclothiazide, thereby counteracting the desired effects.
- 4. Cholestyramine and colestipol decrease the absorption of this
- medication from the gastrointestinal tract. Methyclothiazide should,
- therefore, be taken one hour before or four hours after a dose of
- cholestyramine or colestipol (if one of those medications has also been
- prescribed).
- 5. The side effects of amphotericin B, calcium, cortisone and
- cortisone-like steroids (such as dexamethasone, hydrocortisone, prednisone,
- and prednisolone), digitalis, digoxin, lithium, quinidine, sulfonamide
- antibiotics, and vitamin D may be increased by methyclothiazide.
- BE SURE TO TELL YOUR DOCTOR about any medications you are currently
- taking, especially any listed above.
-
- WARNINGS
-
- * Tell your doctor about unusual or allergic reactions you have had to
- any medications, especially to methyclothiazide or any other sulfa drug,
- including other diuretics, oral antidiabetic medications, or sulfonamide
- antibiotics.
- * Before you start taking methyclothiazide, tell your doctor if you now
- have or if you have ever had kidney disease or problems with urination,
- diabetes mellitus, gout, liver disease, asthma, pancreatic disease, or
- systemic lupus erythematosus.
- * Methyclothiazide can cause potassium loss. Signs of potassium loss
- include dry mouth, thirst, weakness, muscle pain or cramps, nausea, and
- vomiting. If you experience any of these symptoms, call your doctor. To help
- avoid potassium loss, take this drug with a glass of fresh or frozen orange
- juice or cranberry juice or eat a banana every day. The use of a salt
- substitute also helps to prevent potassium loss. Do not change your diet or
- use a salt substitute, however, before discussing it with your doctor. Too
- much potassium can also be dangerous. Your doctor may want to have blood
- tests performed periodically in order to monitor your potassium levels.
- * In order to avoid dizziness or fainting while taking this medication,
- try not to stand for long periods of time; avoid drinking excessive amounts of
- alcohol; and try not to get overheated (avoid strenuous exercise in hot
- weather and do not take hot baths, showers, and saunas).
- * Do not take any over-the-counter (nonprescription) medications for
- weight control or for cough, cold, allergy, asthma, or sinus problems, unless
- your doctor directs you to do so. Some of these products can cause an
- increase in blood pressure.
- * To prevent dehydration (severe water loss) while taking this
- medication, check with your doctor if you have any illness that causes severe
- or continuous nausea, vomiting, or diarrhea.
- * This medication can raise the blood sugar level in diabetic patients.
- Therefore, blood sugar levels should be carefully monitored by blood or urine
- tests when this medication is being taken.
- * Be sure to tell your doctor if you are pregnant. Methyclothiazide can
- cross the placenta and may cause adverse effects in the developing fetus.
- Also, tell your doctor if you are breast-feeding an infant. Although problems
- in humans have not been reported, small amounts of this drug can pass into
- breast milk, so caution is warranted.
-
- ----------------
-
- The material contained here is "FOR INFORMATION ONLY" and should not replace
- the counsel and advice of your personal physician. Promptly consulting your
- doctor is the best path to a quick and successful resolution of any medical
- problem.
-