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CD-ROM Today (UK) (Spanish) 15
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03133.txt
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1994-01-17
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$Unique_ID{BRK03133}
$Pretitle{}
$Title{diphenhydramine}
$Subject{AllerMax Pfeiffer Belix Halsey Benadryl Parke-Davis Kapseals Benylin
Cough Syrup Bydramine Major Compoz Jeffrey Martin Diphen My-K Lab
hydrochloride Dormarex 2 Republic Hydramine Goldline Nervine Nighttime Sleep
Aid Miles Nordryl Vortech Nytol Block Sleep-Eze 3 Whitehall Sominex 2 Beecham
Tusstat Century Twilite Pfeiffer Unisom Nighttime Leeming Antihistamine
sedative/hypnotic diphenhydramine histamine allergic reaction allergy motion
sickness Parkinson's disease nonnarcotic cough suppressant}
$Volume{}
$Log{
Benadryl*0313301.scf}
Benadryl Kapseals*0313302.scf}
Copyright (C) 1993 Publications International, Ltd.
diphenhydramine
------------------------------------------------------------------------------
BRAND NAMES (Manufacturers)
AllerMax (Pfeiffer)
Belix [*] (Halsey)
Benadryl [*] (Parke-Davis)
Benadryl Kapseals (Parke-Davis)
Benylin Cough Syrup [*] (Parke-Davis)
Bydramine Cough Syrup [*] (Major)
Compoz [*] (Jeffrey Martin)
Diphen Cough Syrup [*] (My-K Lab)
diphenhydramine hydrochloride (various manufacturers)
Dormarex 2 [*] (Republic)
Hydramine [*] (Goldline)
Nervine Nighttime Sleep Aid [*] (Miles)
Nordryl (Vortech)
Nytol [*] (Block)
Sleep-Eze 3 [*] (Whitehall)
Sominex 2 [*] (Beecham)
Tusstat (Century)
Twilite [*] (Pfeiffer)
Unisom Nighttime Sleep Aid (Leeming)
* Available over-the-counter (without a prescription)
TYPE OF DRUG
Antihistamine and sedative/hypnotic
INGREDIENT
diphenhydramine
DOSAGE FORMS
Tablets (50 mg)
Capsules (25 mg and 50 mg)
Elixir (12.5 mg per 5-ml spoonful, with 14% alcohol)
Oral syrup (12.5 mg per 5-ml spoonful, with 5% alcohol)
STORAGE
Store at room temperature in a tightly closed container.
USES
Diphenhydramine belongs to a group of drugs known as antihistamines
(antihistamines block the action of histamine, a chemical that is released by
the body during an allergic reaction). It is, therefore, used to treat or
prevent symptoms of allergy. It is also used to treat motion sickness and
Parkinson's disease, and it is used as a nighttime sleeping aid and
nonnarcotic cough suppressant.
TREATMENT
To avoid stomach upset, take diphenhydramine with food, milk, or water
(unless your doctor directs you otherwise).
The elixir and oral syrup forms of this medication should be measured
carefully with a specially designed 5-ml measuring spoon. An ordinary
teaspoon is not accurate enough.
If you miss a dose of this medication, take the missed dose as soon as
possible, unless it is almost time for your next dose. In that case, do not
take the missed dose at all; just return to your regular dosing schedule. Do
not double the next dose.
SIDE EFFECTS
Minor.
Blurred vision; confusion; constipation; diarrhea; dizziness; dry mouth,
throat, or nose; headache; irritability; loss of appetite; nausea;
restlessness; stomach upset; or unusual increase in sweating. These side
effects should disappear as your body adjusts to the medication.
This medication can cause increased sensitivity to sunlight. It is,
therefore, important to avoid prolonged exposure to sunlight and sunlamps.
Wear protective clothing, and use an effective sunscreen.
If you are constipated, increase the amount of fiber in your diet (fresh
fruits and vegetables, salads, bran, and whole-grain breads), exercise, and
drink more water (unless your doctor tells you not to do so).
To reduce mouth dryness, chew sugarless gum or suck on ice chips or a
piece of hard candy.
If you feel dizzy or light-headed, sit or lie down for a while; get up
slowly from a sitting or reclining position, and be careful on stairs.
Major.
Tell your doctor about any side effects that are persistent or
particularly bothersome. IT IS ESPECIALLY IMPORTANT TO TELL YOUR DOCTOR about
changes in menstruation, clumsiness, difficult or painful urination, feeling
faint, flushing of the face, hallucinations, palpitations, ringing or buzzing
in the ears, rash, seizures, shortness of breath, sleeping disorders, sore
throat or fever, tightness in the chest, unusual bleeding or bruising, or
unusual tiredness or weakness.
INTERACTIONS
Diphenhydramine interacts with several other types of medications:
1. Concurrent use of it with other central nervous system depressants
(such as alcohol, barbiturates, benzodiazepine tranquilizers, muscle
relaxants, narcotics, pain medications, and phenothiazine tranquilizers) or
with tricyclic antidepressants can cause extreme drowsiness.
2. Monoamine oxidase (MAO) inhibitors (isocarboxazid, pargyline,
phenelzine, and tranylcypromine) can increase the side effects of this
medication. At least 14 days should separate the use of this drug and the use
of an MAO inhibitor.
3. Diphenhydramine can also interfere with the activity of oral
anticoagulants (blood thinners, such as warfarin) and decrease their
effectiveness.
BE SURE TO TELL YOUR DOCTOR about any medications you are currently
taking, especially any of those listed above.
WARNINGS
* Be sure to tell your doctor about unusual or allergic reactions you
have had to any medications, especially to diphenhydramine or to any other
antihistamine (such as astemizole, azatadine, brompheniramine, carbinoxamine,
chlorpheniramine, clemastine, cyproheptadine, dexchlorpheniramine,
dimenhydrinate, dimethindene, diphenylpyraline, doxylamine, hydroxyzine,
phenidamine, promethazine, pyrilamine, terfenadine, trimeprazine,
tripelennamine, and triprolidine).
* Tell your doctor if you now have or if you have ever had asthma, blood
vessel disease, glaucoma, high blood pressure, kidney disease, peptic ulcers,
enlarged prostate gland, or thyroid disease.
* Diphenhydramine can cause drowsiness or dizziness. Your ability to
perform tasks that require alertness, such as driving a car or operating
potentially dangerous equipment, may be decreased. Appropriate caution
should, therefore, be taken.
* Be sure to tell your doctor if you are pregnant. The effects of this
medication during pregnancy have not been thoroughly studied in humans. Also,
tell your doctor if you are breast-feeding an infant. Small amounts of
diphenhydramine pass into breast milk and may cause unusual excitement or
irritability in nursing infants.
----------------
The material contained here is "FOR INFORMATION ONLY" and should not replace
the counsel and advice of your personal physician. Promptly consulting your
doctor is the best path to a quick and successful resolution of any medical
problem.