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- $Unique_ID{BRK01380}
- $Pretitle{}
- $Title{Precautions With Coumadin}
- $Subject{coumadin bleed heart attack liver warfarin sodium thin blood thinner
- coagulate clots veins venous thrombosis embolism embolisms attacks myocardial
- infarction anticoagulant coagulation vitamin k prothrombin test ptt alcohol
- hemorrhages bleeding clotting infarctions anticoagulants }
- $Volume{D-7}
- $Log{
- Types of Ischemic Strokes I*0006901.scf
- Types of Ischemic Strokes II*0006902.scf
- Types of Hemorrhagic Strokes*0006903.scf}
-
- Copyright (c) 1991-92,1993 Tribune Media Services, Inc.
-
-
- Precautions With Coumadin
-
-
- ------------------------------------------------------------------------------
-
- QUESTION: I take one Coumadin pill a day, and my cardiologist has advised me
- that at the most I am allowed only one drink at night. It suits me fine, but
- I am completely puzzled as to the medical logic behind it. I know that both
- substances are metabolized by the liver, but all my liver function tests are
- normal and I have no bleeding tendencies. Please explain the reason for such
- advice. Thank you.
-
- ------------------------------------------------------------------------------
-
- ANSWER: As you probably know already, Coumadin (also known as warfarin
- sodium) is used to "thin" the blood, reduce its ability to coagulate or form
- clots. It is used either for the prevention of or the treatment of clots in
- the veins (venous thrombosis) and to prevent clots from spreading to all parts
- of the body (embolism) after a heart attack (myocardial infarction). It
- obtains its anticoagulant effect by preventing the formation of various
- coagulation factors that depend upon Vitamin K for their production. When the
- ability of the blood to coagulate is reduced, clots may not form, or if they
- have already formed, they may not grow larger. When a patient is on this
- powerful and effective medication, it is necessary to keep a sharp eye on the
- effect of the medication by checking the blood frequently and determining its
- ability to coagulate. Many circumstances can affect that action including
- travel, changes in diet, environment, physical state of the patient and a wide
- variety of other medications. The test which is used to control the state of
- the blood's ability to coagulate when they are taking Coumadin is called the
- "prothrombin" (PTT) test, which is usually performed on a regular basis while
- the patient is visiting the physician for a follow up examination. Among the
- many substances that can affect the prothrombin response are antibiotics,
- diuretics, thyroid drugs, influenza virus vaccine, and a host of others too
- numerous to mention here. But important among these circumstances (because of
- your question) is alcohol. Both increased and decreased prothrombin time
- responses have been reported when alcohol or diuretics are being taken. That
- makes the control of your blood coagulation more difficult, and leaves you
- open to the risk of unwanted hemorrhages. And that is why your cardiologist
- has advised that you keep the bottle corked.
-
- ----------------
-
- The material contained here is "FOR INFORMATION ONLY" and should not replace
- the counsel and advice of your personal physician. Promptly consulting your
- doctor is the best path to a quick and successful resolution of any medical
- problem.
-
-