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00424.txt
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1994-01-17
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$Unique_ID{BRK00424}
$Pretitle{}
$Title{What Causes Paget's Disease?}
$Subject{Paget's treatment Musculoskeletal Connective Tissue osteitis
deformans hyperactive bone softer bones pelvis thigh skull pain stiffness
headaches loss hearing increasing skull size weariness energy salicylates
nonsteroidal anti-inflammatory medication medications Etidronate disodium
Synthetic salmon calcitonin headache}
$Volume{M-17}
$Log{
Symptoms of Paget's Disease*0007701.scf
Diagnosing and Managing Paget's Disease*0007801.scf}
Copyright (c) 1991-92,1993 Tribune Media Services, Inc.
What Causes Paget's Disease?
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QUESTION: I am a long time sufferer from Paget's Disease, and find it
difficult to believe that all that can be offered as treatment are some simple
pain pills. Can you tell me a bit about this disease, what causes it and what
medications can possibly help me?
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ANSWER: Your desire to know more about your condition makes you the kind of
reader I enjoy responding to, in the hopes that this information can be of
help to you. Paget's disease of the bone (also called osteitis deformans) is
a chronic disease occurring in adults where hyperactive bone is replaced by a
softer bony like structure in various parts of the skeleton, such as the
pelvis, thigh bone and skull. Bone is in a constant state of remodeling, a
process of breakdown and build up. However in Paget's, the new bone is faulty
and can not perform all the duties of normal bone. The cause is unknown, but
about 3% of adults over the age of 40 suffer from the condition, with men more
commonly affected in about a 3 to 2 ratio over women. Many times there are no
symptoms, but when they do occur they include pain, stiffness, headaches, some
loss of hearing, increasing skull size and a general feeling of weariness and
loss of energy. The diagnosis is often made by chance on an x-ray, taken for
other reasons, which shows the typical pattern of bone growth. Generally pain
may be controlled by salicylates and nonsteroidal anti-inflammatory
medications such as ibuprofen. Two other medications are used to successfully
treat and control the condition. Etidronate disodium may be taken in a dose
of 5 to 10 mg per kilogram of body weight, in a single dose each day for 6
months. Synthetic salmon calcitonin may also be effective.
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The material contained here is "FOR INFORMATION ONLY" and should not replace
the counsel and advice of your personal physician. Promptly consulting your
doctor is the best path to a quick and successful resolution of any medical
problem.