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- Document 0656
- DOCN M9620656
- TI Catheter-related cutaneous aspergillosis complicated by fungemia and
- fatal pulmonary infection in an HIV-positive patient with acute
- lymphocytic leukemia.
- DT 9602
- AU Girmenia C; Gastaldi R; Martino P; Department of Human Biopathology,
- University La Sapienza, Rome,; Italy.
- SO Eur J Clin Microbiol Infect Dis. 1995 Jun;14(6):524-6. Unique Identifier
- : AIDSLINE MED/96082797
- AB A case of intravenous catheter-related cutaneous aspergillosis and
- Aspergillus fumigatus fungemia in an HIV-positive patient with
- Burkitt-cell acute lymphocytic leukemia is reported. The patient
- developed pulmonary aspergillosis with a rapidly fatal outcome despite
- recovery from neutropenia and improvement of the underlying malignancy.
- The unusual severity and rapid spread of the infection, despite normal
- neutrophil count and prompt antifungal therapy, suggest that HIV-related
- immunocompromise might play a role in the impairment of host defences
- against Aspergillus infection. Thus catheter-related cutaneous
- aspergillosis could lead to a severe deep-seated infection in
- HIV-positive patients.
- DE Adult Antifungal Agents/THERAPEUTIC USE
- Aspergillosis/*COMPLICATIONS/DRUG THERAPY/ETIOLOGY Case Report
- Catheterization, Central Venous/ADVERSE EFFECTS
- Dermatomycoses/*COMPLICATIONS/DRUG THERAPY/ETIOLOGY Disease Progression
- Fatal Outcome Female Fungemia/*COMPLICATIONS/DRUG THERAPY/ETIOLOGY
- Human Leukemia, Lymphocytic, Acute/*COMPLICATIONS Opportunistic
- Infections/*COMPLICATIONS/DRUG THERAPY Pneumonia/*COMPLICATIONS/DRUG
- THERAPY Support, Non-U.S. Gov't JOURNAL ARTICLE
-
- SOURCE: National Library of Medicine. NOTICE: This material may be
- protected by Copyright Law (Title 17, U.S.Code).
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-