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- THE WEEK, Page 16HEALTH & SCIENCEA Dose of Prevention
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- New research documents folic acid's role in preventing neural
- birth defects
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- The interplay of cells and tissues that marks the growth of an
- embryo is one of nature's most exquisitely orchestrated
- movements. And, for vertebrates, the formation of the spinal
- cord and brain from a simple tube of cells is as crucial to life
- as it is beautiful to contemplate. But any defect in this neural
- tube, likely to appear early in development, can be devastating.
- Among the possible results: anencephaly, in which a baby is
- born minus most of its brain, and spina bifida.
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- In the latest issue of the New England Journal of
- Medicine, a team of researchers from Hungary report that women
- who consume 0.8 mg of folic acid, a B vitamin, for at least a
- month before they conceive have a dramatically lower risk of
- bearing a child with a neural-tube defect. Although the link
- between folic acid and neural-tube defects has been made before,
- this landmark study of 4,156 women is the first to show that the
- malformation can be prevented -- even in women who have no
- previous history of bearing children with neural-tube defects.
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