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- <text id=89TT0214>
- <title>
- Jan. 23, 1989: Bone Booster
- </title>
- <history>
- TIME--The Weekly Newsmagazine--1989
- Jan. 23, 1989 Barbara Bush:The Silver Fox
- </history>
- <article>
- <source>Time Magazine</source>
- <hdr>
- MEDICINE, Page 54
- Bone Booster
- </hdr><body>
- <p>A treatment for osteoporosis
- </p>
- <p> Millions of Americans -- most often older women -- suffer to
- some degree from osteoporosis, the potentially crippling
- affliction that thins the bones and makes them susceptible to
- fractures. When the loss of bone occurs in the spine -- one of
- the most common sites -- patients may experience shortened
- stature, curvature of the back and pain in both the back and
- abdomen. Women who take calcium pills can sometimes prevent the
- onset or progression of the disease, but there has been no
- successful treatment for patients who have substantial bone
- loss.
- </p>
- <p> Last week researchers at the University of Texas
- Southwestern Medical Center at Dallas announced a promising new
- way of increasing bone density that seems to reverse the
- effects of spinal osteoporosis. The treatment relies on sodium
- fluoride, the chemical used by dentists to strengthen teeth and
- in toothpaste to prevent cavities. When the drug was tested
- years ago as a treatment for osteoporosis, it produced severe
- side effects like stomach bleeding, and while the fluoride
- caused bones to thicken, they were still easily broken. But the
- Texas researchers tried giving patients slow-dissolving fluoride
- pills that released the drug only after leaving the stomach.
- The fluoride was administered intermittently and with a calcium
- compound so that the new bone would form gradually and be
- strong. When the preparation was given to 251 women with
- spinal-bone loss, bone mass increased 3% to 6% a year and the
- frequency of vertebral fractures dropped significantly. Side
- effects were minor and occurred in only 5% of the patients. The
- treatment has not been shown to work for osteoporosis of the
- hip or wrist.
- </p>
-
- </body></article>
- </text>
-
-