ocr: ORF Function LI LI protein, major capsid protein L2 L2 protein, minor capsid protein El Initiation of viral DNA replication, helicase, AlPase E2 Transcriptional regulatory protein, auxiliary role in viral DNA replication, complexes E1 E4 Late protein; disrupts cytokeratins E5 Membrane transforming protein; interacts with growth factor receptors (BPV1) E6 Transtorming protein of HPVS; targets degradation of p53; activates telomerase E7 Transforming protein of HPVS; binds to the retinoblastoma protein and other : pocket proteins'