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- FIGURE 8.2-5. The first 44 amino acids of LMP1 engage TNF
- receptor-associated factors 1, 2, and 3 and activate NFkB through
- interaction with TRAF1 and 2. Activation is presumed to proceed by
- constitutive activation of a TRAF2-associated kinase. It is known that
- phosphorylation of IkB leads to degradation of IkB and release of NFkB
- to the nucleus.
-