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   ocr: MULTIPLE MYELOMA Major Criteria Plasmacytoma on tissue biopsy Bone marrow plasmacytosis with >30% plasma cells Monoclonal globulin spike on serum electrophoresis exceeding 3.5 g dLfor G peaks or 2 g/dLf for. A peaks, z1 g/241 hof K- or A-light chain excretion on urine electrophoresis in the presence of amyloidosis Minor Criteria Bone marrow plasmacytosis 10% to 30% plasma cells Monoclonal globulin spike present but less than the level defined above Lytic bone lesions Residual normal IgM <50 mg/dL, IgA < 100 mg/dL, or IgG <600 mg/dL Diagnosis is confirmed when any of the following features are ...