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- FIGURE 4-1. Cell cycle regulators implicated in cancer: highly
- schematic view of points of action of mammalian cyclin CDK complexes
- in the cell cycle. Components implicated in cancer through mutation or
- overexpression (e.g., p53 and cyclin D) or through their absence in
- tumors or transformed cells (e.g., p16 and p21) are screened. (After
- Hunter T, Pines J. Cyclins and cancer. II. Cyclin D and CDK inhibitors
- come of age. (Review) Cell 1994;79:573)
-