ocr: Technique Advantages Disadvantages Fine-needle aspiration Rapid, painless, inexpensive Will not distinguish in situ from invasive cancer No incision prior to selection of local therapy No histologic detail False-negatives and insufficient specimens occur Requires experienced cytopathologists Core biopsy Rapid, painless, inexpensive False-negatives and incomplete characterization of the lesion No incision can OCCuT Can be read by any pathologist Excisional biopsy Complete histology before treatment decision Expensive, more painful, and can be evident cosmetically Avoids false-negatives and insu ...